Spectral-luminescent study of coumarin 35 as fluorescent “light-up” probe for BSA and DNA monitoring

Bayraktutan, Tuğba; Onganer, Yavuz

doi:10.1016/j.dyepig.2017.03.019

Cited by 17 publications

(6 citation statements)

References 34 publications

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“…The linear plot I/I0 vs BSA is shown in Figure 5. Fluorescence titration experiments clearly revealed that there is a linear relationship (R 2 = 0.9872) between the emission intensity and the amount of BSA (0.1 mg/mL to 0.8 mg/mL), which is advantageous for quantitative analysis of [BSA], and the detection limit of GFP for BSA was calculated to be 3.7 nM. This indicates that GFP can be utilized for the detection of the BSA in the nanomolar concentration range.…”

Section: Resultsmentioning

confidence: 99%

The development and application of glyco-probes for bovine serum albumin

Jiang

et al. 2023

Journal of Chemical Research

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Two glyco-probes, GFP and GFN, which are derived from the condensation of 3-acetyl-5-C-(2,3-dihydroxy-1,4-anhydro-β-D-erythro-tetrofuranosyl)-2-methylfuran with benzaldehyde and 1-naphthaldehyde, respectively, are designed and synthesized. Of these two probes, GFP displays a selective and sensitive switch-on fluorescence response towards bovine serum albumin in phosphate-buffered saline over a wide pH range. Moreover, the fluorescence of this probe displays a good linear relationship with the bovine serum albumin concentration ranging from 0 to 0.8 mg/mL, and has a limit of detection as low as 3.7 nM. The stoichiometric ratio of bovine serum albumin /GFP is 1:1. This research paves the way for the development of glyco-probes for bovine serum albumin sensing.

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Section: Resultsmentioning

confidence: 99%

The development and application of glyco-probes for bovine serum albumin

Jiang

et al. 2023

Journal of Chemical Research

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“…BSA is a globular protein and has an important effect on biophysical functions, such as blood circulation and drug binding [ 78 , 79 ]. Two Ir(III) complexes, namely 31 and 32 ( Figure 14 A), were reported by Laskar et al [ 80 ].…”

Section: Specific Response Of Ir(iii) Complexes With Aie Activitymentioning

confidence: 99%

Ir(III) Complexes with AIE Characteristics for Biological Applications

et al. 2022

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Both biological process detection and disease diagnosis on the basis of luminescence technology can provide comprehensive insights into the mechanisms of life and disease pathogenesis and also accurately guide therapeutics. As a family of prominent luminescent materials, Ir(III) complexes with aggregation-induced emission (AIE) tendency have been recently explored at a tremendous pace for biological applications, by virtue of their various distinct advantages, such as great stability in biological media, excellent fluorescence properties and distinctive photosensitizing features. Significant breakthroughs of AIE-active Ir(III) complexes have been achieved in the past few years and great progress has been witnessed in the construction of novel AIE-active Ir(III) complexes and their applications in organelle-specific targeting imaging, multiphoton imaging, biomarker-responsive bioimaging, as well as theranostics. This review systematically summarizes the basic concepts, seminal studies, recent trends and perspectives in this area.

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Section: Introductionmentioning

confidence: 99%

“…The photophysical properties of coumarin chromophore containing conjugates were studied extensively due to their attractive optical properties, such as high quantum yield, AIE behavior, large Stokes shift, solvatochromic behavior, excellent stability and low toxicity. [7][8][9][10][11][12] Recent literature has reported that fluorescent active coumarins have been employed as a fluorescent marker for protein, 13,14 an emissive layer in OLEDs, 15 charge transfer agents 16 and optical whitening agents. 17 Latent fingerprints (LFPs) visualization is very beneficial for the field of forensic science but several powders available for LFP development suffer from low sensitivity, low resolution, low stability and high toxicity.…”

Section: Introductionmentioning

confidence: 99%