It is shown that in a Grothendieck space with the Dunford-Pettis property, the class of well-bounded operators of type (B) coincides with the class of scalar-type spectral operators with real spectrum. It turns out that in such Banach spaces, analogues of the classical theorems of Hille-Sz. Nagy and Stone concerned with the integral representation of Q,-semigroups of normal operators and strongly continuous unitary groups in Hilbert spaces, respectively, are of a very special nature. Various notions of self-adjointness have been developed for operators acting in Banach spaces, each capturing in some respect the basic properties of self-adjointness in Hilbert space. One such notion is that of well-boundedness, a concept introduced by Smart, [17], and first studied by Smart and Ringrose,[15,16,17]; see [8] for a comprehensive treatment of such operators. Well-bounded operators are associated with certain monotone, projection-valued functions on the real line R (not necessarily given by a spectral measure) and have available a form of spectral diagonalization similar to, but in general weaker than, that for selfadjoint operators in Hilbert space, which make them suitable for treating conditional convergence. A slightly stronger notion available is that of well-bounded operator of type (B). Such operators have been intensively studied in various settings by Berkson, Gillespie and others; see Whereas there is a close analogy in certain respect between scalar-type spectral operators with real spectrum, in the sense of Dunford, and well-bounded operators of type (B), there are also fundamental differences, even in the Hilbert space