Spectral, electrochemical, and catalytic properties of a homologous series of manganese porphyrins as cytochrome P450 model: The effect of the degree of β-bromination

GCDCA down-regulates gene expression by increasing Sp1 binding to the NOS-3 promoter in an oxidative stress dependent manner

“…This resulted in an increase in cell survival as measured by the decrease on caspase-3 activity and LDH release. Concerning the use of MnTBAP as a specific superoxide scavenger, it should be noted that non-porphyrin Mn species that appears as impurities in commercial MnTBAP preparations exhibit SOD-like activity and are very effective in dismuting O 2 À [23,24]. Furthermore, the administration of ubiquinone through the mitochondria-targeted antioxidant MitoQ also recovered the activity of the pNOS-3.…”

Biomimetic alkane oxidation by iodosylbenzene and iodobenzene diacetate catalyzed by a new manganese porphyrin: Water effect

“…CarvalhoDa-Silva et al [17] achieved similar results when they used metalloporphyrins bearing (-COOCH 3 ) groups in the para-mesoaryl positions of the porphyrin macrocycle, which may also form hydrogen bonds with water. Therefore, we decided to verify how addition of larger amounts of water to the systems based on PhIO as oxidant affects product yield (Fig.…”

“…On the other hand, In et al [15] have reported that water hydrolyzes PhI(OAc) 2 , to generate PhIO in situ. Silva et al [16] have verified that water enhances catalyst efficiency during cyclohexane oxidation by PhIO and PhI(OAc) 2 , whereas CarvalhoDa-Silva et al [17] have not detected any rise in product yield upon addition of water to systems that employ PhIO as oxidant.…”

“…In the latter case, the bromine atoms introduced into the β-pyrrole positions of the porphyrin ring withdraw electron density from the metal center, to destabilize the high-valent active species. In addition, these same bromine atoms distort the metalloporphyrin macrocycle, which acquires a saddle-type conformation[39] that diminishes selfoxidation and consequent catalyst degradation[9,17,33]. However, comparison of the efficiency of the second-generation cis-[Mn III DAPDPP]Cl with the efficiency of the generation [Mn III (PFTDCPP)]Cl obtained by Doro et al[40] demonstrates that the latter catalyst is much more efficient.…”

Heterogeneous oxidation of the dye Brilliant Green with H 2 O 2 catalyzed by supported manganese porphyrins

“…Increased awareness of environmental regulations has led scientists to search for catalysts that can help to remediate effluents. In this context, the proven capacity of metalloporphyrins (MP), in solution [7][8][9] or immobilized on inorganic supports [10][11][12], to catalyze the oxidation of different organic substrates in the presence of oxygen donors such as hydrogen peroxide, peroxyacids, and dioxygen [13,14] has motivated studies on the catalytic activity of MP in the degradation of dyes [15][16][17].…”