Spectra of Positrons Lifetimes in Choose Gel Drugs

Abstract

Spectra of positrons lifetimes in selected gel non-steride analgesic and antiphlogistic drugs were investigated. The basic components in them were sodium salts of diclophenac and they differed from one another with the chemical composition of other components. It was found that in all of the investigated spectra there occurred a component which testified to the formation of positronium. The differences in the values of ortho-Ps component lifetimes and their intensity can be attributed to the presence of ingredients modifying the effects of the drug.

Applications of Positron Annihilation Spectroscopy to Life Science

“…Different o-Ps lifetimes were observed in selected gels containing non-steroidal analgesic and antipyretic drugs; observed lifetime differences were attributed to the differing types of drug in combination with the gel. [41]. The mechanisms of the plasticizing effects of PEG 400 on methylcellulose (Metolose) cast films were found different from the low to high concentration [42].…”