Specificity of glucose oxidase (notatin)

Keilin, D.; Hartree, E. F.

doi:10.1042/bj0500331

Cited by 197 publications

(36 citation statements)

References 14 publications

(30 reference statements)

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“…Furthermore,-once glucose is destroyed, pentose can be determined by the standard orcinol reaction without glucose interference. Glucose oxidase is relatively specific for glucose (22), acting upon its D-,B-glucopyranose form (23), converting it to D-gluconolactone, and generating peroxide in the reaction. Several commercial preparations of glucose oxidase are available, all containing mutarotase (which catalyzes the interconversion of a and fi-glucopyranose) and catalase (which destroys the peroxide).…”

Section: Analytical Proceduresmentioning

confidence: 99%

Physiological Disposition and Metabolic Fate of Infused Pentoses in Man

Wyngaarden¹,

Segal²,

Foley³

1957

J. Clin. Invest.

107

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Section: Analytical Proceduresmentioning

confidence: 99%

Physiological Disposition and Metabolic Fate of Infused Pentoses in Man

Wyngaarden¹,

Segal²,

Foley³

1957

J. Clin. Invest.

107

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“…2,4-dinitrophenylate was measured spectrophotometrically at 360 m# (molecular extinction coefficient, 14,600). When glucose was present, it interfered with the quantitative hydrolysis of the dinitrobenzenes and was, therefore, removed with glucose oxidase (23).…”

Section: Ct4-labdled 24-dinitrobo~zenesil-cl~-dncb and 1-ci~-dnbsoamentioning

confidence: 99%

A Study of the Distribution of 2,4-Dinitrobenzene Sensitizers Between Isolated Lymph Node Cells and Extracellular Medium in Relation to Induction of Contact Skin Sensitivity

Eisen

Kern

Newton

et al. 1959

The Journal of Experimental Medicine

117

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Many protein conjugates, prepared in vitro with reactive simple chemicals, are highly effective reagents for inducing the formation of antibodies which are specific for the simple chemical components of the conjugates (1). Antibodies may also be formed directly in response to injections of certain simple chemicals, providing the simple substances used are capable of reacting in vivo to form protein conjugates (24). These generalities are only partly applicable to the induction of contact skin sensitivity. In order for simple chemicals to induce the latter hypersensitive state, the in ~vo formation of protein conjugates (6, 7) is also obligatory (5). However, with a few possible exceptions (8), protein conjugates prepared in ~itro have little, if any, capacity to induce contact skin sensitivity (9). Part of the present work is devoted to the presentation of evidence which supports and extends older observations (8, 9) concerning the unexpected inability of protein conjugates, made in tritro, to induce contact skin sensitivity. The different conditions required for induction of antibody formation and for induction of contact skin sensitivity constitute an interesting distinction between these two inducible responses. But this difference introduces a problem in respect to induction of contact skin sensitivity: If the formation in vivo of protein conjugates is obligatory, why are "synthetic" conjugates, prepared in the test tube,

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“…The encapsulation and entrapment of enzymes into the aqueous lumen of polymersomes has attracted broad interest for potential application in biomimetic organelles, nanoreactors, and enzyme‐directed prodrug therapy . It is well known that many oxidases (e.g., glucose oxidase, GOx, and xanthine oxidase, XO) catalyze production of H 2 O 2 under an aerobic condition . In this context, Sommerdiijk, Napoli, Hubbell, and coworkers explored GOx‐encapsulated PEG 16 ‐ b ‐PPS 50 ‐ b ‐PEG 16 polymersomes as self‐destructing vesicles based on the GOx‐catalyzed conversion of β‐D‐glucose and O 2 into gluconolactone and H 2 O 2 .…”

Section: Ronss‐responsive Polymersomesmentioning

confidence: 99%

Reactive Oxygen, Nitrogen, and Sulfur Species (RONSS)‐Responsive Polymersomes for Triggered Drug Release

Deng

Liu

2017

Macromol. Rapid Commun.

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Reactive oxygen, nitrogen, and sulfur species (RONSS) are cross-reacting and involved in a myriad of physiological and pathological processes. Similar to acidic pH, overexpressed enzymes, and other specific stimuli found in pathological microenvironments, RONSS are recognized as a category of emerging triggering events and have been employed to design activatable theranostic nanomaterials. In this regard, a plethora of RONSS-responsive nanovectors including polymeric micelles and vesicles (also referred to as polymersomes) are constructed. In comparison with micelles, polymersomes comprising aqueous interiors enclosed by hydrophobic membranes show intriguing applications in synergistic delivery of both hydrophobic and hydrophilic drugs, nanoreactors, and artificial organelles. This feature article focuses on the recent developments in the fabrication of RONSS-responsive polymersomes and their potential biomedical applications in terms of triggered drug delivery.

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Specificity of glucose oxidase (notatin)

Cited by 197 publications

References 14 publications

Physiological Disposition and Metabolic Fate of Infused Pentoses in Man

Physiological Disposition and Metabolic Fate of Infused Pentoses in Man

A Study of the Distribution of 2,4-Dinitrobenzene Sensitizers Between Isolated Lymph Node Cells and Extracellular Medium in Relation to Induction of Contact Skin Sensitivity

Reactive Oxygen, Nitrogen, and Sulfur Species (RONSS)‐Responsive Polymersomes for Triggered Drug Release

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