“…Inhibitors of glycohydrolases do not have to be transition state mimetics of the enzyme-catalyzed hydrolysis of the glycosidic bond . Compound that do not resemble sugars such as (−)-(3a S ,5 S ,6 S ,6a R )-3a,5,6,6a-tetrahydro-5,6-isopropylidenedioxyfuro[2,3- d ]isoxazole-3-methanol inhibits β-galactosidase from Aspergillus niger ( K i = 18 μM) and that from Aspergillus orizae ( K i = 72 μM) specifically (uncompetitive inhibition) . The neutral C-disaccharide α-C(1→3)-mannopyranoside of N -acetylgalactosamine is a inhibitor of β-galactosidase from jack bean ( K i = 7.5 μM, mixed mode of inhibition) …”