Specific sublingual immunotherapy with peach LTP (Pru p 3). One year treatment: a case report

Pereira, Celso; Bartolomé, B; Asturias, J A; Ibarrola, Iñaki; Tavares, Beatriz; Loureiro, Graça; Machado, Daniel; Chieira, C

doi:10.1186/1757-1626-0002-0000006553

Cited by 19 publications

(17 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Few papers have been published concerning peach sublingual immunotherapy and none with the specific target of legume desensitization. In 2009, Pereira et al described a LTPs-allergic patient who presented a negative double-blind placebo-controlled food challenge -acumulative dose of 150 grams of fresh peach-and a secondary good tolerance of legumes after four months of native Pru p3 specific sublingual immunotherapy with a maintenance dose of 200 µg of nPru p3 per month [10], similar to our monthly dose of 280 µg. One year later Garcia BE et al demonstrated changes in peach allergic patientsr Pru p3 IgE levels and in peach and apple extract SPT induced by a six month period of peach sublingual immunotherapy [11].…”

Section: Short Communicationmentioning

confidence: 61%

See 1 more Smart Citation

Sublingual Immunotherapy with Quantified Peach Extract: An Alternative Treatment in Legumes Allergy

Moreno¹

2014

J Vaccines Vaccin

View full text Add to dashboard Cite

Section: Short Communicationmentioning

confidence: 61%

“…Subsequently we undertook an open oral challenge with lentil and chickpea. We used lentil and chickpea soups in progressively increasing doses (1,5,10,30,75, and 125 mL) every 15 minutes according to previous studies [6]. Both challenges were negative.…”

Section: Short Communicationmentioning

confidence: 99%

Sublingual Immunotherapy with Quantified Peach Extract: An Alternative Treatment in Legumes Allergy

Moreno¹

2014

J Vaccines Vaccin

View full text Add to dashboard Cite

“…There are some interesting cases showing the efficiency of this treatment, but there are no commercially available immunotherapies for these patients. 25 …”

Section: Discussionmentioning

confidence: 99%

Recurrent anaphylaxis in patient allergic to eggplant – a case study

Ukleja-Sokołowska

Gawrońska-Ukleja

Żbikowska-Gotz

et al. 2017

Asian Pac J Allergy Immunol

View full text Add to dashboard Cite

Eggplant allergy is rare and most of the previously described reactions were mild. In this case report, we present an interesting case of a 27-year-old male who experienced symptoms of anaphylaxis (shortness of breath, and swelling of the face, lips and tongue, which was followed by hypotension, tachycardia of 140/min and a sudden loss of consciousness) several minutes after eating a dish containing backed eggplant. Previously, the patient had experienced symptoms of allergy after eating different types of food, such as salad and chicken in spices. The symptoms were enhanced by co-factors. They were heterogeneous, ranging from oral symptoms to anaphylactic shock.During the diagnostic pathway, skin prick tests (SPTs) were positive to grass and cat. Prick by prick skin tests were positive for eggplant, both cooked and fresh. In ImmunoCap ISAC, IgE specific to rPhl p 1 (1.7 ISU-E), rCan f 5 (1,2 ISU-E), Fel d 1 (9.6 ISU-E ) and LTPs -nJug r 3 (0.5 ISU-E), rPru p 3 (0.6 ISU-E), rPla a 3 (1.3 ISU-E) were found.Based on the clinical pattern of the disease and the results of component resolved diagnosis, we suspect that this complex case of anaphylaxis may be gathered with LTP syndrome.

show abstract

“…Pereira et al (12) published a case report of a woman with a positive allergological work-up for LTP and cross-reacting vegetable foods. The patient underwent SLIT for one year with efficacy and safety.…”

Section: Discussionmentioning

confidence: 99%

“…In literature, data on profilin content in plant-derived foods are lacking and for this reason we chose the maintenance dose of 100llg/mi weekly because 50llg/ml of profilin was the allergen concentration needed to induce a wheal double in size to the one induced by histamine at l Omg/ml in our patients (12).…”

Section: Discussionmentioning

confidence: 99%

Profilin Desensitization in Two Patients with Plant-Derived Food Allergy

Nucera

Aruanno

Rizzi

et al. 2012

Int J Immunopathol Pharmacol

View full text Add to dashboard Cite

Profilins are "panallergens", responsible for many cross-reactivities between inhalant, latex and plant-derived food allergens. We evaluated the effectiveness and the safety of sublingual desensitization treatment (SLIT) in two patients with allergic respiratory and food diseases. Skin prick tests, IgE and IgG4 assays to pollens, some plant-derived foods, profilin, non-lipid specific transfer protein and PR 10 proteins were performed. The patients also underwent double-blind placebo-controlled challenge (DBPCFC) with the culprit foods and profilin and then a SLIT with it. Both the patients had positive SPT, specific IgE and DBPCFCs with profilin and some vegetables referred in anamnesis. They therefore underwent SLIT with profilin extract. At the end of treatment, the patients had negative DBPCFCs with culprit foods and a decrease of specific IgE levels for profilin and vegetable foods. Profilin desensitization allowed our patients to manage their diet without restriction, eating several foods previously not tolerated.

show abstract

Specific sublingual immunotherapy with peach LTP (Pru p 3). One year treatment: a case report

Abstract: Introduction: Food allergy is an increasing problem with limited therapeutic approaches apart from to the eviction diet.

Cited by 19 publications

References 15 publications

Sublingual Immunotherapy with Quantified Peach Extract: An Alternative Treatment in Legumes Allergy

Sublingual Immunotherapy with Quantified Peach Extract: An Alternative Treatment in Legumes Allergy

Recurrent anaphylaxis in patient allergic to eggplant – a case study

Profilin Desensitization in Two Patients with Plant-Derived Food Allergy

Contact Info

Product

Resources

About