Specific language impairment in an adult with type I bipolar disorder: a case report

Mattos, Paulo; Rabelo, Beatriz; Gueiros, Fernanda; Soares, Tania; Coutinho, Gabriel

doi:10.1590/s1516-44462009000200023

Cited by 1 publication

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“…Some clinical studies have reported the presentation of specific language impairment (SLI) in patients with bipolar disorder, suggesting that deficiencies in verbal functions are among the most outstanding. For example, interpretation, writing, and oral comprehension are presented as being below the expected considering the age and intellectual coefficient (Mattos, Rabelo, Gueiros, Soares, & Coutinho, 2009). Alterations in verbal fluency, both formal and semantic fluency, have also been reported in patients with bipolar disorder (Radanovic, Nunes, Gattaz, & Forlenza, 2008).…”

Section: Importance Of Language Disorders In Psychiatric Diseasesmentioning

confidence: 94%

FOXP2 and language alterations in psychiatric pathology

et al. 2019

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Background. From the first reports of the linguist Noam Chomsky it has become clear that the development of language has an important genetic component. Several reports in families have shown the relationship between language disorders and genetic polymorphisms. The FOXP2 gene has been a fundamental piece for the understanding of language development. This gene codes for a transcription factor containing a forkhead domain of DNA binding and participates in the regulation of the expression of a large number of genes involved in the embryonic development of fundamental neuronal structures needed for the development of speech and language. Objective. To present an updated view of the relationship between FOXP2 and language alterations in psychiatric pathology. Method. Narrative review of information reported in databases on the recent advances supporting genetic participation in language disorders of psychiatric illness. Results. Update of content related to FOXP2 and its participation in language alterations in psychiatric diseases. Discussion and conclusion. Advances in the genetic study of language disorders in psychiatric pathology open up new avenues of investigation that allow us to explore how language emerged and how it evolved, as well as to carry out comparative studies on the structure and functioning of genes to approach the understanding of this complex characteristic that makes us human.

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Section: Importance Of Language Disorders In Psychiatric Diseasesmentioning

confidence: 94%