Specific detection of avidin–biotin binding using liquid crystal droplets

Khan, Mashooq; Park, Soo‐Young

doi:10.1016/j.colsurfb.2015.01.047

“…The interfacial properties of the liquid crystals are essential for the development of display technologies [1,3]. On the other hand, the nematic anchoring in the nematic-vapour interface, together with the elastic properties of the liquid crystal, are determinant to understand the conformation of nematic droplets [4][5][6], which have applications in molecular sensing [7][8][9][10] or electro-optic devices such as privacy windows [11][12][13][14][15][16]. From a microscopic point of view, the interfacial anchoring is well known to be determined by the intermolecular potential details.…”

Section: Introductionmentioning

confidence: 99%

Computer simulation study of the nematic–vapour interface in the Gay–Berne model

Rull

¹

,

Romero-Enrique

²

2017

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We present computer simulations of the vapour-nematic interface of the GayBerne model. We considered situations which correspond to either prolate or oblate molecules. We determine the anchoring of the nematic phase and correlate it with the intermolecular potential parameters. On the other hand, we evaluate the surface tension associated to this interface. We find a corresponding states law for the surface tension dependence on the temperature, valid for both prolate and oblate molecules.

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“…With fluorescent dye molecules dispersed in the layered structure inside the droplet, a dye microlaser that emits the laser light in all directions is obtained. Because the orientation of liquid crystal molecules at interfaces is very sensitive to the outside environment, LC droplets and flat films have been used to detect a variety of quantities [13], including temperature [14,15], electric [9] and magnetic field, pH [14,16], glucose [16,17], surfactants [18], endotoxins [19], proteins [20,21] and biological properties [22]. Even slight change of molecular orientation at the interface produces strong changes throughout the liquid crystal layer.…”

Section: Introductionmentioning

confidence: 99%

Remote and autonomous temperature measurement based on 3D liquid-crystal microlasers

Pirnat

¹

,

Humar

²

,

Muševič

³

2019

Emerging Liquid Crystal Technologies XIV

0

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We demonstrate non-contact temperature measurement with one tenth of a kelvin precision at distances of several meters using omnidirectional laser emission from dye-doped cholesteric liquid crystal droplets freely floating in a fluid medium. Upon the excitation with a pulsed laser the liquid crystal droplet emits laser light due to 3D Bragg lasing in all directions. The spectral position of the lasing is highly dependent on temperature, which enables remote and contact-less temperature measurement with high precision. Both laser excitation and collection of light emitted by microlasers is performed through a wide telescope aperture optics at a distance of up to several meters. The optical excitation volume, where the droplets are excited and emitting the laser light is of the order of ten cubic millimeters. The measurement is performed with ten second accumulation time, when several droplets pass through the excitation volume due to their motion. The time of measurement could easily be shortened to less than a second by increasing the rate of the excitation laser. Since the method is based solely on measuring the spectral position of a single and strong laser line, it is quite insensitive to scattering, absorption and background signals, such as autofluorescence. This enables a wide use in science and industry, with a detection range exceeding tens of meters.

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“…Because the orientation of liquid crystal molecules at interfaces is very sensitive to the outside environment, LC droplets and flat films have been used to detect a variety of quantities [13], including temperature [14,15], electric [9] and magnetic field, pH [14,16], glucose [16,17], surfactants [18], endotoxins [19], proteins [20,21] and biological properties [22]. Even slight change of molecular orientation at the interface produces strong changes throughout the liquid crystal layer.…”

Section: Introductionmentioning

confidence: 99%

Remote and autonomous temperature measurement based on 3D liquid crystal microlasers

Pirnat¹,

Humar²,

Muševič³

2018

View full text Add to dashboard Cite

We demonstrate non-contact temperature measurement with one tenth of a kelvin precision at distances of several meters using omnidirectional laser emission from dye-doped cholesteric liquid crystal droplets freely floating in a fluid medium. Upon the excitation with a pulsed laser the liquid crystal droplet emits laser light due to 3D Bragg lasing in all directions. The spectral position of the lasing is highly dependent on temperature, which enables remote and contact-less temperature measurement with high precision. Both laser excitation and collection of light emitted by microlasers is performed through a wide telescope aperture optics at a distance of up to several meters. The optical excitation volume, where the droplets are excited and emitting the laser light is of the order of ten cubic millimeters. The measurement is performed with ten second accumulation time, when several droplets pass through the excitation volume due to their motion. The time of measurement could easily be shortened to less than a second by increasing the rate of the excitation laser. Since the method is based solely on measuring the spectral position of a single and strong laser line, it is quite insensitive to scattering, absorption and background signals, such as autofluorescence. This enables a wide use in science and industry, with a detection range exceeding tens of meters.

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Specific detection of avidin–biotin binding using liquid crystal droplets

Cited by 51 publications

References 27 publications

Computer simulation study of the nematic–vapour interface in the Gay–Berne model

Computer simulation study of the nematic–vapour interface in the Gay–Berne model

Remote and autonomous temperature measurement based on 3D liquid-crystal microlasers

Remote and autonomous temperature measurement based on 3D liquid crystal microlasers

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