Specific allergy to <i>Penaeus monodon</i> (seawater shrimp) or <i>Macrobrachium rosenbergii</i> (freshwater shrimp) in shrimp‐allergic children

Jirapongsananuruk, Orathai; Sripramong, Chaweewan; Pacharn, Punchama; Udompunturak, S.; Chinratanapisit, Sasawan; Piboonpocanun, Surapon; Visitsunthorn, Nualanong; Vichyanond, Pakit

doi:10.1111/j.1365-2222.2008.02979.x

Cited by 59 publications

(89 citation statements)

References 21 publications

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“…However, these were a minority, and this is one main finding of the present multicenter study. This is in keeping with the observation that some of the shrimp allergens mentioned above, namely sarcoplasmic calcium-binding protein and myosin light chain, seem to play a more relevant role in the pediatric population [14,15], whereas all our patients were adults. However, in other adult populations the prevalence of sensitization to myosin light chain, arginine kinase or sarcoplasmic calcium-binding proteins largely exceeded that found in our patients [18].…”

Section: Discussionsupporting

confidence: 48%

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Shrimp Allergy in Italian Adults: A Multicenter Study Showing a High Prevalence of Sensitivity to Novel High Molecular Weight Allergens

Asero

Mistrello

Amato

et al. 2011

Int Arch Allergy Immunol

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Background: Shrimp is a frequent cause of food allergy worldwide. Besides tropomyosin, several allergens have been described recently. Objective: We investigated which allergens are involved in Italian shrimp-allergic adults. Methods: Sera from 116 shrimp-allergic patients selected in 14 Italian allergy centers were studied. Skin prick tests with house dust mite (HDM) as well as measurements of IgE to Pen a 1 (shrimp tropomyosin) and whole shrimp extract were performed. All sera underwent shrimp immunoblot analysis, and inhibition experiments using HDM extract as inhibitor were carried out on some Pen a 1-negative sera. Results: Immunoblots showed much variability. IgE reactivity at about 30 kDa (tropomyosin) was found in <50% of cases, and reactivity at about 67 kDa and >90 kDa was frequent. Further reactivities at 14–18, 25, 43–50, about 60 and about 80 kDa were detected. Most subjects had a history of shrimp-induced systemic symptoms irrespective of the relevant allergen protein. IgE to Pen a 1 were detected in sera from 46 (41%) patients. Skin reactivity to HDM was found in 43/61 (70%) Pen 1-negative subjects and inhibition studies showed that pre-adsorption of sera with HDM extract induced a marked weakening of the signal at >67 kDa. Conclusions: Several allergens other than tropomyosin are involved in shrimp allergy in adult Italian patients. Some hitherto not described high molecular weight allergens seem particularly relevant in this population and their cross-reactivity with HDM allergens makes them novel potential panallergens of invertebrates.

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Section: Discussionsupporting

confidence: 48%

“…As a consequence, in view of possible allergenic differences with freshwater shrimps [15], fresh shrimps belonging to these seawater species were employed to carry out both in vivo and in vitro tests.…”

Section: Methodsmentioning

confidence: 99%

Shrimp Allergy in Italian Adults: A Multicenter Study Showing a High Prevalence of Sensitivity to Novel High Molecular Weight Allergens

Asero

Mistrello

Amato

et al. 2011

Int Arch Allergy Immunol

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“…(14) Clinical management is problematic due to the unpredictability of its reaction, which varies with the species of shellfish, the quantity eaten, the body part affected, and possibly, the preparation method. (15)(16)(17) In addition, its abundant use in Asian cooking, together with poor food labelling practices in Singapore, (18) makes accidental ingestion of shellfish difficult to avoid.…”

Section: Specific Food Allergies In Singaporementioning

confidence: 99%

Food allergy in Singapore: opening a new chapter

Lee¹

2014

smedj

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R ev iew A r tic le 244 I NTRO D U C TIO NSingapore has rapidly evolved into a modernised city state and currently faces the health burden of noncommunicable diseases (NCDs), resembling that of developed Western nations.(1) In children, allergic diseases, including food allergy, are among the most common NCDs.(2) Food allergy rates are reported to be more than 10% in challenge-proven studies among Australian infants, (3) while in the United Kingdom (UK) (4) and the United States of America (USA), Singapore have not met the expected rise experienced by other highly industrialised countries, it is also uncertain whether the food allergy epidemic will hit our nation. This unclear prediction, together with ever-changing cultural practices and eating habits due to immigration and overseas influence, has opened a new chapter of food allergy in Singapore.A PubMed search of the terms "food allergy" and "Singapore" generated a total of 45 results from January 1999 to January 2014. All the articles generated are in English. Of these, 12 articles are not food-allergy focused, and two are focused on food testing methodology that is not unique to Singapore. Of the remaining 31 articles found, 16 are studies conducted on children, and 9 are review articles on food allergy in Asia or Singapore. EPID EM IO LO GYIn Asia, food allergy data is just beginning to emerge, providing no satisfactory trend. One study from Chongqing, China, reported a doubling in the challenge-proven prevalence rates from 3.5% to 7.7% among 0-2-year-olds over a ten-year period. (8) Conversely, a South Korean study reported that the prevalence of food allergy symptoms in 6-12-year-olds had decreased from 10.9% to 8.9% over five years.(9) Preliminary findings in an ongoing study of young Singaporean children aged 11-30 months demonstrated that overall, self-reported food allergy prevalence could be as high as 5.4% (Lee AJ, unpublished). Unfortunately, the only prior data for comparison was in 6-12-year-olds, where the rates (also by questionnaire) were estimated to be 4%-5% in 1999.Given that the prevalence of food allergy tends to decrease with age, using this data, we surmise that food allergy has probably not increased in Singapore over a 14-year period. SPECIFIC FOOD ALLERGIES IN SINGAPOREWorldwide and regional differences in food allergies mainly depend on diet and culture (although this may not always be the case). For example, shellfish is the most common food allergen in Singapore and is ubiquitous in Southeast Asia, likely by virtue of its high consumption. However, fish, also eaten abundantly in Singapore, is a rare allergen here. Allergy to egg and cow's milk, despite their high consumption worldwide, is comparatively lower in Singapore than in the West. The reverse is true of peanut allergy, which is epidemic in the West compared to Asia. However, the pattern of food allergy in Singapore appears to have changed over the last decade, with peanut allergy increasing in prevalence and being the most common cause of anaphylaxis in Singaporean childr...

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“…Then 50 毺g of prawn extract was applied to immobilized non-linear pH [3][4][5][6][7][8][9][10] gradient strip of 7 cm length for rehydration overnight (12)(13)(14) h). Isoelectric focusing was run at 20 曟 using the Protean IEF Cell Apparatus (BioRad, USA) with the following voltage/time gradient: 100 V for 1 min, 250 V for 30 min, 4 000 V for 2 h and 4 000 V for 10 000 V-h. Before transferring the IPG strip onto the second dimension, the strip was equilibrated sequentially for 10 min in a buffer containing 65 mM dithio-threitol and then 135 mM iodoacetamide in 125 mM Tris-HCl, pH 6.8, 6 M urea, 2% SDS, 30% glycerol and 0.01% bromophenol blue.…”

Section: Two-dimensional (2-de) Gel Electrophoresismentioning

confidence: 99%

“…Among shellfish allergies, prawn is the most frequent culprit [2,3] . Sensitized individuals can develop urticaria, angioedema, laryngospasm, asthma and life-threatening anaphylaxis [4,5] .…”

Section: Introductionmentioning

confidence: 99%

Identification of the major allergen of Macrobrachium rosenbergii (giant freshwater prawn)

Yadzir

Misnan

Abdullah

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

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Specific allergy to Penaeus monodon (seawater shrimp) or Macrobrachium rosenbergii (freshwater shrimp) in shrimp‐allergic children

Abstract: Specific allergy to Pm or Mr was confirmed by food challenges. SPT using crude extracts and the PTP test are useful tools for screening shrimp sensitization before a food challenge. The predictive probability of SPT is helpful where a food challenge is not feasible.

Cited by 59 publications

References 21 publications

Shrimp Allergy in Italian Adults: A Multicenter Study Showing a High Prevalence of Sensitivity to Novel High Molecular Weight Allergens

Shrimp Allergy in Italian Adults: A Multicenter Study Showing a High Prevalence of Sensitivity to Novel High Molecular Weight Allergens

Food allergy in Singapore: opening a new chapter

Identification of the major allergen of Macrobrachium rosenbergii (giant freshwater prawn)

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