Species C rotavirus infections in asymptomatic piglets in India, 2009-2013: Genotyping and phylogenetic analysis of all genomic segments

Abstract

Asymptomatic infection with Rotavirus C (RVC) at 20 percent detection rate was recorded in pigs from India. Sequencing of the VP6, VP7, and NSP4 genes of RVC strains identified I7/ I10, G1 and E5 genotypes, respectively. Full genome sequencing of one of these strains revealed additional P1, R1, C1, M3, A1, N5, T5, H1 genotypes, of VP4, VP1, VP2, VP3, NSP1, NSP2, NSP3, NSP5 genes, respectively. Detection of porcine RVC strains at two different locations in India and at different time points strongly suggests their continuous circulation in the pig population through asymptomatic infections.