Speciation of vanadium present in a model yeast system

Abstract

Yeast cells were used as a model system for the investigation and identification of toxic forms of vanadium obtained on dosing a nutrient medium with various known vanadium species. Total vanadium uptake by the yeast cells was in the region of 10 p.p.m. when the nutrient medium was dosed with 200 p.p.m. of the toxic species V V prepared as a V205 -NaOH solution. No cetl growth was observed in the nutrient medium when the concentrations were above 200 p.p.m. However, vanadium was found to accumulate in the yeast cells to a much greater extent when the nutrient medium was dosed with solutions of the less toxic form V l V . Total vanadium in the cells was determined using flame atomic absorption spectrometry.

A highly sensitive spectrophotometric determination of micro amounts of vanadium(V) in environmental and alloy samples by using 3,4-dihydroxybenzaldehydeisonicotinoylhydrazone (3,4-DHBINH)

“…The toxicity of vanadium depends upon its oxidation state. Vanadium is more toxic in +5 oxidation state than in +4 state (Patel et al 1990). Threshold limit values (TLV) reported is 0.5 mg/m 3 of air and 0.1 mg/m 3 of fume (Kolthoff et al 1971).…”

Supervanadophile: Complexation, preconcentration and transport studies of vanadium by octa functionalized calix[4]resorcinarene-hydroxamic acid

“…However, it becomes toxic when its concentration exceeds 0.5 ppm. The toxicity of vanadium is dependent on its oxidation state, with vanadium(V) being more toxic than vanadium(IV) [21].…”

Spectrophotometric determination of vanadium using variamine blue and its application to synthetic, environmental and biological samples

“…The toxicity of vanadium is dependent on its oxidation state, with vanadium(V) being more toxic than vanadium(IV) [1]. Vanadium in trace amounts is an essential element for cell growth at g l -1 levels, also has been shown to inhibit cholesterol synthesis and to increase the oxidation of fatty acids of higher concentrations.…”