Speciation of organotin compounds in environmental samples with semi-permanent coated capillaries by capillary electrophoresis coupled with inductively coupled plasma mass spectrometry

Abstract

A novel method using capillary electrophoresis (CE) coupled with inductively coupled plasma mass spectrometry (ICP-MS) for the separation of four organotin compounds has been developed. Semipermanent coating of dioctadecyl dimethyl ammonium chloride (DDAC) was applied and investigated to enhance separation efficiency of trimethyltin (TMT) chloride, tributyltin (TBT) chloride, dibutyltin (DBT) dichloride and monobutyltin (MBT) trichloride. The electrolyte composition and ionic strength were optimized. Running buffer containing 0.608 mol L À1 HAc and 7 mmol L À1 NaAc was selected for the separation. The detection limits of the four organotin compounds ranged from 0.037 to 0.112 mg L À1 (as Sn) and the values of the relative standard deviation (RSD) were below 3.1% for migration time, less than 7.8% for peak height and not more than 8.4% for peak area. The developed method was successfully applied for speciation analysis of four organotin compounds in one certified reference material (CRM 477, mussel tissue), and environmental samples including water samples, grape wine and biological samples (Mya arenaria Linnaeus). The determined values (as organotin compounds) of CRM 477 (1.81 AE 0.13 (TBT), 1.36 AE 0.16 (DBT), 1.17 AE 0.18 (MBT)) were in good agreement with the certified values (2.20 AE 0.19 (TBT), 1.54 AE 0.12 (DBT), 1.50 AE 0.28 (MBT)). 0.325 mg L À1 MBT and 1.02 mg g À1 (as Sn) TBT were found in grape wine and Mya arenaria Linnaeus samples.

Speciation analysis of arsenic compounds by capillary electrophoresis on-line coupled with inductively coupled plasma mass spectrometry using a novel interface

“…It is required to maintain a stable electrical circuit from CE to nebulizer, introduce CE effluent into ICP-MS efficiently and keep a low dead volume [21,22]. Currently, typical sheath flow-based interfaces are commonly used, which combine a commercial nebulizer and commercially available tee or cross designed fittings to connect the CE capillary, the Pt electrode, the additional sheath flow liquid and the nebulizer of ICP-MS [23][24][25][26]. Generally, a sheath flow liquid (also called makeup solution) is needed in the interface in order to provide closed electrical circuit and increase the total liquid flow to match the nebulizer flow rate.…”

Atomic spectrometry methods for wine analysis: A critical evaluation and discussion of recent applications

“…The applicability and suitability of the method for wine analysis was demonstrated and contamination by butyl-, phenyl-and octyltins was found in the wines analyzed [135]. In a recently published paper Sun et al reported on the use of capillary electrophoresis coupled with ICPMS for the determination of trimethyltin, tributyltin, dibutyltin and monobutyltin in wines [146]. Furthermore, the suitability of SPE and FAAS for Mn partitioning in wines has been demonstrated by Pohl, who found that Mn is predominantly present in the form of cationic species [147].…”

Characterization of interactions between organotin compounds and human serum albumin by capillary electrophoresis coupled with inductively coupled plasma mass spectrometry

“…The diagram of the interface of CE-ICP-MS used in the experiment has been published elsewhere [21]. As previously illuminated, analytical conditions have to be fit for metal complex stability constant determination.…”

“…The schematic diagram for the instrument of CE-ICP-MS system has been published elsewhere [10,19,21]. In brief, the separations of the ACE and NECEEM methods were operated on HP 3D CE system (Agilent, Germany).…”

“…Detailed diagram of interface used in this study could be found elsewhere [21]. Briefly, a Pt electrode, a sheath flow and the CE capillary were introduced into the interface based on a cross design.…”