Special Issue “Reproductive Health Concerns for Women”

Yang, Szu‐Ting; Lee, Wen-Ling; Wang, Peng Hui

doi:10.3390/life11111274

Cited by 3 publications

(2 citation statements)

References 23 publications

(34 reference statements)

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“…Although suction curettage is generally considered safe, it can cause significant morbidity and mortality when complications occur [17][18][19] and result in deterioration of women's reproductive health and possible economic or social problems. 20 Notably, pregnancies complicated by life-limiting malformations, such as trisomy 18 and 13, are frequently associated with placental abnormalities, [21][22][23][24][25] and excessive hemorrhage may also occur during suction curettage. Such cases should be treated with caution and managed appropriately if antenatally diagnosed.…”

Section: Introductionmentioning

confidence: 99%

The timing of intravenous oxytocin administration is crucial to minimize perioperative blood loss during first-trimester suction curettage for missed abortion

Yang

Chang

Chao

et al. 2022

Journal of the Chinese Medical Association

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Background: Oxytocin is commonly used to reduce blood loss during suction curettage for missed abortion. However, the potential of oxytocin to mitigate blood loss in early pregnancy remains controversial. Based on the hypothesis that the “timing” of oxytocin administration may be a critical factor, we investigated whether the timing of intravenous (IV) administration is associated with reduced perioperative blood loss during first-trimester suction curettage for missed abortion. Methods: The medical charts of 146 patients with ultrasound-confirmed first-trimester missed abortion who underwent suction curettage with IV oxytocin administration were retrospectively reviewed. Results: Among the patients, 67 received 10 IU of IV oxytocin before suction curettage (early-oxytocin administration group), while 79 patients received 10 IU of IV oxytocin after suction curettage (late-oxytocin administration group). The demographic features between the two groups did not significantly differ. However, there was a lower proportion of nulliparous patients in the early-oxytocin administration group than in the late-oxytocin administration group (38.8% vs 60.8%, p = 0.006). The perioperative blood loss amount was significantly lower in the early-oxytocin administration group than in the late-oxytocin administration group (60 [range: 50–100] vs 100 [range: 30–250] mL, p = 0.001). Moreover, the multivariate logistic regression analysis showed that the early-oxytocin administration group had a lower risk for a perioperative blood loss amount of ≥100 mL than the late-oxytocin administration group (0.23 [range: 0.10–0.55], p = 0.001); a gestational age of 9–12 weeks (p = 0.009) was found to be associated with an increased risk for a perioperative blood loss amount of ≥100 mL. Conclusion: Compared with late-oxytocin administration, early-oxytocin administration could reduce perioperative blood loss during first-trimester suction curettage for missed abortion. However, the results require further investigation.

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Section: Introductionmentioning

confidence: 99%

The timing of intravenous oxytocin administration is crucial to minimize perioperative blood loss during first-trimester suction curettage for missed abortion

Yang

Chang

Chao

et al. 2022

Journal of the Chinese Medical Association

Self Cite

View full text Add to dashboard Cite

show abstract

“…1 Therefore, the policy to encourage couples to get pregnancy and subsequently offering a better care for maternal-fetal wellbeing before, during, and after pregnancy is of paramount importance. [2][3][4][5][6] Many efforts have been conducted, but the morbidity and mortality of women during pregnancy and perinatal morbidity and mortality are still high in Taiwan. 1 Among these, premature preterm birth (PPB) has been one of the critical causes resulting in the high morbidity and mortality of both mothers and infants.…”

mentioning

confidence: 99%