Special Issue “Bacillus subtilis as a Model Organism to Study Basic Cell Processes”

Barák, Imrich

doi:10.3390/microorganisms9122459

Cited by 3 publications

(1 citation statement)

References 11 publications

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“…In the majority of biotechnology and microbiology labs, E. coli was regarded as a model organism. Normal Bacillus subtilis is a gram-positive, rod-shaped, aerobic, non-pathogenic soil bacterium that primarily affects some animals' gastrointestinal tracts (GITs) (Bar, 2021).…”

Section: Introductionmentioning

confidence: 99%

In Vitro Screening of Selected Medicinal Plants for Their Anti-bacterial Efficacy Against Few Clinical Isolates

Sharmah¹,

Manickam²,

Chaubey

et al. 2023

Preprint

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From ancient times, plants have been the primary source of several phytochemicals that have been crucial in maintaining human health. A variety of antibiotics including secondary metabolites that plants produce while under stress. Due to the advent of several multi-drug resistant strains, commonly available antibiotics lost their effectiveness, and it became the second biggest cause of death globally. It was critical to create brand-new, highly efficient antibacterial medications from plant sources that were affordable, had fewer side effects, and worked quickly to treat bacterial illnesses. This study examines the effectiveness of nine methanolic plant extracts against nine bacterial diseases that are frequently caused by bacteria.

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Section: Introductionmentioning

confidence: 99%

In Vitro Screening of Selected Medicinal Plants for Their Anti-bacterial Efficacy Against Few Clinical Isolates

Sharmah¹,

Manickam²,

Chaubey

et al. 2023

Preprint

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Characterization of heat, salt, acid, alkaline, and antibiotic stress response in soil isolate Bacillus subtilis strain PSK.A2

Kadapure,

Dalbanjan,

S K

2024

Int Microbiol

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Nature should be the model for microbial sciences

Baker,

Hyde,

Leão

2024

J Bacteriol

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Until recently, microbiologists have relied on cultures to understand the microbial world. As a result, model organisms have been the focus of research into understanding Bacteria and Archaea at a molecular level. Diversity surveys and metagenomic sequencing have revealed that these model species are often present in low abundance in the environment; instead, there are microbial taxa that are cosmopolitan in nature. Due to the numerical dominance of these microorganisms and the size of their habitats, these lineages comprise mind-boggling population sizes upward of 10 28 cells on the planet. Many of these dominant groups have cultured representatives and have been shown to be involved in mediating key processes in nature. Given their importance and the increasing need to understand changes due to climate change, we propose that members of Nitrosophaerota ( Nitrosopumilus maritimus ), SAR11 ( Pelagibacter ubique ), Hadesarchaeia, Bathyarchaeia, and others become models in the future. Abundance should not be the only measure of a good model system; there are other organisms that are well suited to advance our understanding of ecology and evolution. For example, the most well-studied symbiotic bacteria, like Buchnera , Aliivibrio , and Rhizobium , should be models for understanding host-associations. Also, there are organisms that hold new insights into major transitions in the evolution of life on the planet like the Asgard Archaea (Heimdallarchaeia). Innovations in a variety of in situ techniques have enabled us to circumvent culturing when studying everything from genetics to physiology. Our deepest understanding of microbiology and its impact on the planet will come from studying these microbes in nature. Laboratory-based studies must be grounded in nature, not the other way around.

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Special Issue “Bacillus subtilis as a Model Organism to Study Basic Cell Processes”

Abstract: Bacillus subtilis has served as a model microorganism for many decades [...]

Cited by 3 publications

References 11 publications

In Vitro Screening of Selected Medicinal Plants for Their Anti-bacterial Efficacy Against Few Clinical Isolates

In Vitro Screening of Selected Medicinal Plants for Their Anti-bacterial Efficacy Against Few Clinical Isolates

Characterization of heat, salt, acid, alkaline, and antibiotic stress response in soil isolate Bacillus subtilis strain PSK.A2

Nature should be the model for microbial sciences

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