Spatiotemporal regulation of Pseudorabies Virus Thymidine kinase UL23 by post-translational modification
Chuang Li,
Rui Cao,
Rui Zhang
et al.
Abstract:Post-translational modification plays a significant role in the interaction between viruses and their hosts. The pseudorabies virus (PRV) is a highly contagious herpesvirus that affects the central nervous system and respiratory tract of swine. However, the role of post-translational modifications, including Ubiquitination and SUMOylation, in host and PRV interplays is poorly understood. Here we examined the SUMO modification of PRV proteins and revealed that the PRV thymidine kinase UL23 can undergo SUMO modi… Show more
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