Spatiotemporal Organization of Functional Cargoes by Light-Switchable Condensation in Escherichia coli Cells
Fang Pan,
Han Zu,
Ya-Jiao Zhu
et al.
Abstract:Biomolecular condensates
are dynamic subcellular compartments that
lack surrounding membranes and can spatiotemporally organize the cellular
biochemistry of eukaryotic cells. However, such dynamic organization
has not been realized in prokaryotes that naturally lack organelles,
and strategies are urgently needed for dynamic biomolecular compartmentalization.
Here we develop a light-switchable condensate system for on-demand
dynamic organization of functional cargoes in the model prokaryotic Escherichia coli ce… Show more
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