2000
DOI: 10.1016/s0022-3956(00)00017-0
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Spatiotemporal gait patterns during over ground locomotion in major depression compared with healthy controls

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Cited by 204 publications
(151 citation statements)
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References 27 publications
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“…As some of the formerly depressed patients were taking antidepressant medication, we cannot rule out the possibility that these medications might have affected our results. However, it should be noted that previous studies on antidepressant medication have found either no effects on gait parameters (Lemke et al, 2000) or small changes that were in the direction of the never-depressed gait pattern reported in our study (i.e., increased gait speed; Paleacu et al, 2007). Thus, it seems rather unlikely that the group differences found in our study are attributable to medication effects.…”
Section: Discussioncontrasting
confidence: 77%
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“…As some of the formerly depressed patients were taking antidepressant medication, we cannot rule out the possibility that these medications might have affected our results. However, it should be noted that previous studies on antidepressant medication have found either no effects on gait parameters (Lemke et al, 2000) or small changes that were in the direction of the never-depressed gait pattern reported in our study (i.e., increased gait speed; Paleacu et al, 2007). Thus, it seems rather unlikely that the group differences found in our study are attributable to medication effects.…”
Section: Discussioncontrasting
confidence: 77%
“…A number of studies have investigated gait patterns of currently depressed patients, and results have provided empirical evidence for a close relationship between gait and depression/depressed mood. (Bader, Bühler, Endras, Klippstein, & Hell, 1999;Lemke, Wendorff, Mieth, Buhl, & Linnemann, 2000;Paleacu, Shutzman, Giladi, Herman, Simon, & Hausdorff, 2007;Sloman, Berridge, Homatidis, Hunter, & Duck, 1982;Sloman, Pierynowski, Berridge, Tupling, & Flowers, 1987). For example, in a comprehensive three-dimensional analysis of gait characteristics in patients suffering from a current episode of MDD, five features most strongly differentiated gait of currently depressed from never-depressed participants (Michalak, Troje, Fischer, Vollmar, Heidenreich, & Schulte, in press).…”
mentioning
confidence: 99%
“…Existing studies have found reduced gait speed [8][9][10], reduced step or stride length [9,11], increased step width and increased double support phase (DSP) [9] in those with FOF but similar changes are observed with increasing age [12,13], depression [14] and with a history of falls [15], all of which are also associated with FOF. Rochat et al [16] found similar gait changes between groups with no FOF, FOF alone and FOF with activity restriction but while the differences between the no FOF and FOF alone groups were fully explained by confounding variables, those with FOF and activity restriction had decreased gait performance and increased gait variability independent of health and functional status.…”
Section: Introductionmentioning
confidence: 92%
“…The most common sources of normative data are those collected on "control" groups that are included in studies on pathological gait patterns for the purpose of comparison. Examples include elderly fallers, people with depression, detoxified alcoholic men, and hemiplegia [13][14][15][16] Because the aim of rehabilitation is to restore function, a normative database of gait parameters is desirable. This is a large task because the database must account for the broad spectrum of what is regarded as normal, including differences not just in gender and age but also among people in different geographical locations and of different cultural backgrounds [17].…”
Section: Introductionmentioning
confidence: 99%