Spatiotemporal expression and coexpression patterns of SRPK1 in the human brain: A neurodevelopmental perspective
Jing‐jing Wang,
Sagor Kumar Roy,
Yu‐ming Xu
Abstract:BackgroundSRPK1 is a splicing‐related protein that plays an important role in the development and function of the human brain. This article presents evidence that SRPK1 has distinct spatiotemporal expression patterns enriched in processes related to neurodevelopmental disorders across development.Material and methodWe used the BrainSpan growing mammalian brain transcriptome to evaluate the distribution of SRPK1 throughout the entire brain. RNA‐sequencing data were gathered from 524 tissue samples recovered fro… Show more
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