The eruption of the COVID-19 epidemic has engendered significant public health security perils, representing a grave menace to human well-being and vitality, while also exerting a profound impact on economic and societal spheres [1,2]. The virus has afflicted humanity through modes of respiratory droplet and contact transmission. To mitigate the proliferation of the virus, the Chinese government has actively carried out nucleic acid testing [3], which has also spawned research on optimizing the transport path of new coronavirus testing samples. Thus, the investigation into the conveyance path of these samples bears immense practical significance. The sample transfer process commonly entails healthcare personnel collecting samples at diverse testing sites, followed by the imperative dispatch of vehicles from the testing center to gather these samples. However, due to the variability in sample quantities, collection times, and frequencies, this results in an inefficacious utilization of vehicle cargo space and the proliferation of circuitous paths, thereby inflating transshipment costs. Certain testing sites may be inaccessible via vehicular means, necessitating