Spatial variation of bone biomechanical properties around a dental implant using nanoindentation: a case study

Yoon, Hyung‐In; Jeon, Min-Jeong; Kim, Hye-Lee; D, Kim; Han, Jung‐Suk

doi:10.1016/j.jmbbm.2017.12.027

Cited by 6 publications

(9 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The initial bone formation in L1 may be explained by the fact that L1 corresponds to locations where the local stress field is likely to be the most important compared to other ROIs since mechanical loading is known to trigger bone formation [2]. This result is in agreement with a previous paper [8] showing that the bone elastic properties measured using nanoindentation around a dental implant are higher around the upper parts of implant threading, where stresses are the most important.…”

Section: Discussionsupporting

confidence: 89%

“…where the Poisson's ratio of bone tissue νb = 0.3 was chosen based on [8,31,35]. the bone ratio BA/TA is significantly lower for the far group compared to the close group (Fig.…”

Section: Local Density Estimationmentioning

confidence: 99%

“…The resulting bone mechanical properties can be assessed at different length scales, e.g. microscopically with nanoindentation [8,9] or globally through implant pullout [10].…”

Section: Introductionmentioning

confidence: 99%

“…Nanoindentation has been also used to measure the elastic properties of engineered bone obtained by transplantation of scaffolds seeded with mesenchymal stem cells [25,26], and to evaluate the effect of bone tissue mineral content [27], nanostructure [28] and anisotropy on the microscopic elastic properties, both experimentally and numerically [29,30]. The elastic properties of bone tissue at the BII have also been characterized around dental implants to assess the effect of implant material and surface treatment [31][32][33], of location around the implant [8,32], of mechanical loading [34] and of bone maturation and healing [33,35]. In another in vivo model where a titanium plate has been subperiosteally implanted into cortical bone, nanoindentation has been used to characterize the differences of elastic properties between bone tissue developing at the implant surface and mature bone [36].…”

Section: Introductionmentioning

confidence: 99%

“…Multimodal analysis has proven its effectiveness to characterize multiple bone properties in sitematched locations at the BII [8,[45][46][47]. expressed as the ratio of the Young's modulus and of the square of the ultrasonic velocity, which represents a powerful approach to retrieve mass density variations at the scale of several micrometers [45].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Multimodal Evaluation of the Spatiotemporal Variations of Periprosthetic Bone Properties

Fraulob

Cann

Voumard

et al. 2020

Journal of Biomechanical Engineering

View full text Add to dashboard Cite

Titanium implants are widely used clinically. However, surgical failures still occur because of a lack of implant stability. Periprosthetic biomechanical bone properties need to be characterized to better understand osseointegration phenomena and anticipate implant failures. The aim of this study was toinvestigate the spatio-temporal variations of i) the indentation modulus E* and ii) the wave velocity v of newly formed bone tissue. Eight coin-shaped Ti6Al4V implants were inserted into rabbit tibiae for 7 and 13 weeks. This in vivo model allowed to distinguish mature and newly formed bone and to work in a standardized configuration. Nanoindentation, histological analysis and micro-Brillouin scattering measurements were carried out to assess the indentation modulus E*, the BA/TA (bone area/total area) and the wave velocity v, respectively, at different locations relatively to the implant surface. This approach allowed to determine the relative variation of bone mass density at the microscopic scale. All measured parameters (E*, v, ? and BA/TA) are found to be higher in the vicinity of the implant and for higher healing duration, suggesting increased mineralization. The indentation modulus is 12.3 % (respectively 3.2 %) higher in the close than in the far groups and 14.4 % (respectively 2.8 %) higher in the lateral than in the central groups after 7 weeks (respectively 13 weeks) of healing, leading to similar evolution of the bone mass density. These results lead to a bone spreading pathway confirmed by histology consistent with contact osteogenesis phenomena.

show abstract

Section: Discussionsupporting

confidence: 89%

“…where the Poisson's ratio of bone tissue νb = 0.3 was chosen based on [8,31,35]. the bone ratio BA/TA is significantly lower for the far group compared to the close group (Fig.…”

Section: Local Density Estimationmentioning

confidence: 99%

“…The resulting bone mechanical properties can be assessed at different length scales, e.g. microscopically with nanoindentation [8,9] or globally through implant pullout [10].…”

Section: Introductionmentioning

confidence: 99%