Spatial transcriptomic patterns underlying amyloid-β and tau pathology are associated with cognitive dysfunction in Alzheimer’s disease

Yu, Meichen; Risacher, Shannon L.; Nho, Kwangsik T.; Wen, Qiuting; Oblak, Adrian L.; Unverzagt, Frederick W.; Apostolova, Liana G.; Farlow, Martin R.; Brosch, Jared R.; Clark, David G.; Wang, Sophia; Deardorff, Rachael; Wu, Yu-Chien; Gao, Sujuan; Sporns, Olaf; Saykin, Andrew J.

doi:10.1016/j.celrep.2024.113691

Cell Reports

2024

DOI: 10.1016/j.celrep.2024.113691

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Spatial transcriptomic patterns underlying amyloid-β and tau pathology are associated with cognitive dysfunction in Alzheimer’s disease

Meichen Yu,

Shannon L. Risacher,

Kwangsik T. Nho

et al.

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Spatial transcriptomic patterns underlying amyloid-β and tau pathology are associated with cognitive dysfunction in Alzheimer’s disease

Cited by 2 publications

References 123 publications

Integrating amyloid and tau imaging with proteomics and genomics in Alzheimer’s disease

Integrating amyloid and tau imaging with proteomics and genomics in Alzheimer’s disease

Regional vulnerability to Aβ and tau pathology

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