Spatial Single Cell Profiling Using Imaging Mass Cytometry: Inflammatory Versus Penetrating Crohn’s Disease
Malte Lehmann,
Benjamin Weixler,
Sefer Elezkurtaj
et al.
Abstract:Background and aims
Fistula formation is a major complication in Crohn’s disease (CD) and the role of the immune cell compartment remains to be elucidated. Thus, we compared the immune-cell compartment of CD fistula to inflammatory CD colitis using imaging mass cytometry and immunofluorescence.
Methods
A 36-marker panel including structural, functional and lineage markers for use in imaging mass cytometry (IMC) was establishe… Show more
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