Spatial resolution of confocal XRF technique using capillary optics

Dehlinger, Maël; Fauquet, C.; Lavandier, Sébastien; Aumporn, Orawan; Jandard, F.; Arkadiev, Vladimir A.; Bjeoumikhov, A.; Tonneau, D.

doi:10.1186/1556-276x-8-271

Cited by 18 publications

(12 citation statements)

References 22 publications

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“…Our concept of ultra-compact fiber-integrated X-ray dosimeter is first demonstrated with the fully calibrated X-ray focusing bench shown in Fig. 1 [25]. Polychromatic X-ray radiation from a low power Rh target lab source (800 µA at 35 kV) is focused with a polycapillary lens into a 25 µm wide spot (FWHM, manufacturer's data).…”

Section: Resultsmentioning

confidence: 99%

Ultracompact x-ray dosimeter based on scintillators coupled to a nano-optical antenna

Xie¹,

Maradj²,

Suárez³

et al. 2017

Opt. Lett.

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High energy radiations are nowadays cornerstone in scientific, medical and industrial imaging and cancer therapy. However, their detection and dosimetry are restricted to systems of modest compactness that are not compatible with endoscopy. Here, we report the first experimental imaging and dosimetry of X-rays with an ultracompact sensor integrated at the end of a single mode optical fiber (125 µm full diameter). We realize such a dosimeter by coupling luminescent scintillators to a nano-optical antenna engineered at the end of the fiber and by detecting in-fiber outcoupled luminescence with a photon counter. Direct profile and real-time dosimetry of a X-ray focused beam reveals a spatial resolution of a few microns together with a sensitivity better than 10 3 X-photons/s/µm 2 at energies of 8-10 keV. Because the nano-optical platform is auto-aligned with respect to the fiber, the resulting dosimeter is plug-and-play, flexible, and it is suitable for ultralow footprint endoscopic investigations at higher X-ray energies. Our nano-optical approach thus offers the possibility of X-ray profiling and dosimetry in ultra-confined environments, opening up new avenues in the fields of X-ray imaging, real-time control of cancer radiotherapies and Curie therapies, medical and industrial endoscopy, etc. With this study, nano-optical antennas make a first key contribution to the development of X-ray sensing protocols and architectures.

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Section: Resultsmentioning

confidence: 99%

Ultracompact x-ray dosimeter based on scintillators coupled to a nano-optical antenna

Xie¹,

Maradj²,

Suárez³

et al. 2017

Opt. Lett.

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“…For example, the confocal XRF technology can base on a PFXRL in the excitation channel and a cylindrical monocapillary with radii ranging from 50 μm down to 5 μm in the detection channel to improve spatial resolution (Dehlinger et al 2013b). The extrapolated value for a 0.5-μm radius capillary suggests that sub-1-μm resolution XRF should be possible with a laboratory source.…”

Section: Trends Of Confocal Xrfmentioning

confidence: 99%

“…Of course, increasing the source brightness, i.e. working with liquid-metal or synchrotron sources, could probably lead to reaching 100-nm resolution (Dehlinger et al 2013b). The confocal XRF facility can base on Fresnel zone plates in the excitation channel and a PPXRL in the detection channel.…”

Section: Trends Of Confocal Xrfmentioning

confidence: 99%

Confocal X-ray technology based on capillary X-ray optics

Sun¹,

Ding²

2015

Reviews in Analytical Chemistry

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Capillary X-ray optics is versatile, and it can be used with synchrotron radiation source, conventional X-ray source, laser-plasma ultrafast X-ray source, and so forth. Recently, the confocal X-ray technology based on capillary X-ray optics has become popular, and it has been widely used in X-ray fluorescence, X-ray absorption fine structure, X-ray diffraction, small-angle X-ray scattering, X-ray imaging, and X-ray scattering. This confocal X-ray technology has applications in many fields, including environmental monitoring, food science, life science, chemistry, physics, nanomaterials, nondestructive test, security check, and so on.

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“…In x-ray fluorescence (XRF) analysis, mono- and poly-capillary optics were usually used to focus x-ray beams with a focal spot diameter as small as 22 μm. 10 In XLCT, Cong et al . proposed a dual cone scanning method with a poly-capillary lens, in which the x-ray beam was focused into a spot with a diameter less than 50 μm.…”

Section: Introductionmentioning

confidence: 99%

Collimated superfine x-ray beam based x-ray luminescence computed tomography

Zhang

Zhu

Lun

et al. 2017

XST

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X-ray luminescence computed tomography (XLCT) is a hybrid imaging modality with the potential to achieve a spatial resolution up to several hundred micrometers for targets embedded in turbid media with a depth larger than several millimeters. In this paper, we report a high spatial resolution XLCT imaging system with a collimated superfine x-ray beam in imaging the deeply embedded targets. A collimator with a 100 micrometer pinhole was mounted in the front of a powerful x-ray tube to generate a superfine x-ray pencil beam with a beam diameter of 0.175 mm. For the phantom experiment of four capillary targets with an edge-to-edge distance of 400 micrometers, we were able to reconstruct the targets in a depth of 5 mm successfully, which were validated with microCT images. We have further investigated the effect of different x-ray beam diameters on the reconstructed XLCT images with numerical simulations. Our results indicate that XLCT has the ability to image successfully multiple deeply embedded targets when the collimated x-ray beam diameter is less than or equal to the target edge-to-edge distance. Our numerical simulations also demonstrate that XLCT can achieve a spatial resolution of 200 micrometers for targets embedded at a depth of 5 mm if the scanning beam has a diameter of 100 micrometers.

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Spatial resolution of confocal XRF technique using capillary optics

Cited by 18 publications

References 22 publications

Ultracompact x-ray dosimeter based on scintillators coupled to a nano-optical antenna

Ultracompact x-ray dosimeter based on scintillators coupled to a nano-optical antenna

Confocal X-ray technology based on capillary X-ray optics

Collimated superfine x-ray beam based x-ray luminescence computed tomography

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