Spatial regulation of synthetic and biological nanoparticles by DNA nanotechnology

Yang, Zhongqiang; Liu, Huajie; Li, Dongsheng

doi:10.1038/am.2015.2

Cited by 22 publications

(13 citation statements)

References 95 publications

(82 reference statements)

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“…[4] Although there has been remarkable progress in the synthesis of nanoparticles (NPs) with controlled size,shape,and composition, [5] thegoal of precise functionalization of NPs for the creation of molecule-like discrete nanostructures with customized shape and design is yet to be achieved. [6] Fore xample,D NA has been exploited in the functionalization of various types of nanomaterials,i ncluding metals (for example,A u, Ag), [7] semiconductors (such as,q uantum dots and polymer dots), [8] insulators (for example,u pconversion and metal oxides), NPs, [9] and arange of carbon nanomaterials. [6] Fore xample,D NA has been exploited in the functionalization of various types of nanomaterials,i ncluding metals (for example,A u, Ag), [7] semiconductors (such as,q uantum dots and polymer dots), [8] insulators (for example,u pconversion and metal oxides), NPs, [9] and arange of carbon nanomaterials.…”

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confidence: 99%

“…As ar esult of its ability to recognize nonparallel base-pairing,DNA can be used as part of ah ighly flexible programmable route for the construction of nanostructures,a nd it has recently received increased attention for this purpose. [6] Fore xample,D NA has been exploited in the functionalization of various types of nanomaterials,i ncluding metals (for example,A u, Ag), [7] semiconductors (such as,q uantum dots and polymer dots), [8] insulators (for example,u pconversion and metal oxides), NPs, [9] and arange of carbon nanomaterials. [1a, 10] DNA-functionalized gold NPs (DNA-AuNPs) are among the most studied nanobiological systems.…”

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confidence: 99%

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Transfer of Two‐Dimensional Oligonucleotide Patterns onto Stereocontrolled Plasmonic Nanostructures through DNA‐Origami‐Based Nanoimprinting Lithography

et al. 2016

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The precise functionalization of self-assembled nanostructures with spatial and stereocontrol is am ajor objective of nanotechnology and holds great promise for many applications.H erein, the nanoscale addressability of DNAo rigami was exploited to develop ap recise copymachine-like platform that can transfer two-dimensional oligonucleotide patterns onto the surface of gold nanoparticles (AuNPs) through ad eliberately designed toehold-initiated DNAd isplacement reaction. This strategy of DNA-origamibased nanoimprinting lithography (DONIL) demonstrates high precision in controlling the valence and valence angles of AuNPs.These DNA-decorated AuNPs act as precursors in the construction of discrete AuNP clusters with desired chirality.

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confidence: 99%

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confidence: 99%

Transfer of Two‐Dimensional Oligonucleotide Patterns onto Stereocontrolled Plasmonic Nanostructures through DNA‐Origami‐Based Nanoimprinting Lithography

et al. 2016

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“…The structural diversity of DNA nanoarchitectures is the most attractive feature of DNA nanotechnology. From the application perspective, DNA nanotechnology can be divided into static and dynamic categories [42,43]. In static DNA nanotechnology, the DNA strands are immobilized within particular geometries, patterns, or crystals that facilitate the positional assembly of nanoparticles along the DNA nanostructures [42].…”

Section: Diversity In Dna Nanoarchitecturesmentioning

confidence: 99%

“…From the application perspective, DNA nanotechnology can be divided into static and dynamic categories [42,43]. In static DNA nanotechnology, the DNA strands are immobilized within particular geometries, patterns, or crystals that facilitate the positional assembly of nanoparticles along the DNA nanostructures [42]. The dynamic DNA nanotechnology includes DNA nanomachines with potential applications ranging from sensing to delivery and robotics [43].…”

Section: Diversity In Dna Nanoarchitecturesmentioning

confidence: 99%

Molecular architectonics of DNA for functional nanoarchitectures

Ghosh¹,

Datta²,

Govindaraju³

2020

Beilstein J. Nanotechnol.

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DNA is the key biomolecule central to almost all processes in living organisms. The eccentric idea of utilizing DNA as a material building block in molecular and structural engineering led to the creation of numerous molecular-assembly systems and materials at the nanoscale. The molecular structure of DNA is believed to have evolved over billions of years, with structure and stability optimizations that allow life forms to sustain through the storage and transmission of genetic information with fidelity. The nanoscale structural characteristics of DNA (2 nm thickness and ca. 40–50 nm persistence length) have inspired the creation of numerous functional patterns and architectures through noncovalent conventional and unconventional base pairings as well as through mutual templating-interactions with small organic molecules and metal ions. The recent advancements in structural DNA nanotechnology allowed researchers to design new DNA-based functional materials with chemical and biological properties distinct from their parent components. The modulation of structural and functional properties of hybrid DNA ensembles of small functional molecules (SFMs) and short oligonucleotides by adapting the principles of molecular architectonics enabled the creation of novel DNA nanoarchitectures with potential applications, which has been termed as templated DNA nanotechnology or functional DNA nanoarchitectonics. This review highlights the molecular architectonics-guided design principles and applications of the derived DNA nanoarchitectures. The advantages and ability of functional DNA nanoarchitectonics to overcome the trivial drawbacks of classical DNA nanotechnology to fulfill realistic and practical applications are highlighted, and an outlook on future developments is presented.

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“…By modifying DNA strands, nanomaterial can be linked with each other and become dimer, trimer, satellite etc., [22] which facilitates the construction of various multifunctional nanodevices and biological sensors. [30] Figure 1 (A) Scheme of temperature-dependent reversible plasmonic circular dichroism responses based DNA modified AuNRs (yellow rod) (Reprinted with permission. [38] Copyright 2012, American Chemical Society).…”

Section: Smart Linkermentioning

confidence: 99%

Applications of DNA Nanotechnology in Synthesis and Assembly of Inorganic Nanomaterials

Yang

Wei

et al. 2016

Chin. J. Chem.

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In addition to its inherited genetic function, DNA is one of the smartest and most flexible self-assembling nanomaterials with programmable and predictable features, for which, more and more scientists combine DNA with nanomaterials and put them into designing, synthesizing and assembling. In this review, four modes of action of DNA molecules are introduced in a figurative and intuitive way, based on the four different roles it plays in synthesis and assembly of nanomaterials: (a) smart linkers to guide nanoparticle assembly, (b) 2D or 3D scaffold with well-designed binding sites, (c) nucleation sites to directly facilitate Au/Pd/Ag/Cu nanowires, nanoparticles, nanoarrays and (d) serving as capping agents to prevent crystal growth, and control size and morphology. To be sure, this state-of-the-art combination of functional DNA molecules and inorganic nanomaterials greatly encouraged step towards the development of analytical science, life science, environmental science, and other promising field they can address. DNA-guided nanofabrication will eventually exceed expectations far beyond our scope in the near future.

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Spatial regulation of synthetic and biological nanoparticles by DNA nanotechnology

Cited by 22 publications

References 95 publications

Transfer of Two‐Dimensional Oligonucleotide Patterns onto Stereocontrolled Plasmonic Nanostructures through DNA‐Origami‐Based Nanoimprinting Lithography

Transfer of Two‐Dimensional Oligonucleotide Patterns onto Stereocontrolled Plasmonic Nanostructures through DNA‐Origami‐Based Nanoimprinting Lithography

Molecular architectonics of DNA for functional nanoarchitectures

Applications of DNA Nanotechnology in Synthesis and Assembly of Inorganic Nanomaterials

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