Spatial neurolipidomics—MALDI mass spectrometry imaging of lipids in brain pathologies
Durga Jha,
Kaj Blennow,
Henrik Zetterberg
et al.
Abstract:Given the complexity of nervous tissues, understanding neurochemical pathophysiology puts high demands on bioanalytical techniques with respect to specificity and sensitivity. Mass spectrometry imaging (MSI) has evolved to become an important, biochemical imaging technology for spatial biology in biological and translational research. The technique facilitates comprehensive, sensitive elucidation of the spatial distribution patterns of drugs, lipids, peptides, and small proteins in situ. Matrix‐assisted laser … Show more
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