1993
DOI: 10.1016/0006-8993(93)91744-d
|View full text |Cite
|
Sign up to set email alerts
|

Spatial memory and stereotypic behaviour of animals in radial arm mazes

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
6
0

Year Published

1996
1996
2019
2019

Publication Types

Select...
5
2

Relationship

0
7

Authors

Journals

citations
Cited by 18 publications
(6 citation statements)
references
References 17 publications
0
6
0
Order By: Relevance
“…Our behavioral studies with the eight-arm radial maze task demonstrated impairment of spatial working memory, which requires a fully functional hippocampus (Lanke et al, 1993;Hodges, 1996;Pothuizen et al, 2004), in maternally stressed adult offspring. As shown in Figure 2A, the impaired ability of maternally stressed mice to learn to reduce arm-revisiting errors as the training proceeds in the radial arm maze indicates that they have deficits in this one-experience learning.…”
Section: Discussionmentioning
confidence: 74%
See 1 more Smart Citation
“…Our behavioral studies with the eight-arm radial maze task demonstrated impairment of spatial working memory, which requires a fully functional hippocampus (Lanke et al, 1993;Hodges, 1996;Pothuizen et al, 2004), in maternally stressed adult offspring. As shown in Figure 2A, the impaired ability of maternally stressed mice to learn to reduce arm-revisiting errors as the training proceeds in the radial arm maze indicates that they have deficits in this one-experience learning.…”
Section: Discussionmentioning
confidence: 74%
“…To examine whether chronic maternal stress has a long-lasting influence on hippocampus-dependent learning and memory, we assessed the effects of maternal stress on the performance of adult offspring in the spatial working memory version of the eight-arm radial maze task, which is known to be dependent on the hippocampus (Lanke et al, 1993;Hodges, 1996). In each session, mice had to visit each of the eight arms only once to earn the greatest reward, because reentry of an arm already visited was not rewarded and was counted as a working memory error.…”
Section: Impaired Spatial Memory But Normal S-r Habit Learning In Matmentioning
confidence: 99%
“…7) is further evidence of disrupted learning behavior. Impaired spatial/associative learning in rats has been shown to result in animals choosing arms in the maze in a stereotypic manner (sequentially entering adjacent arms), reflecting a shift from the more efficient allocentric stimulusresponse learning strategy (utilizing environmental cues) to a preconditioned ''default'' egocentric strategy (preference of direction) to recover the bait reward (Lanke et al, 1993;Soblosky et al, 1996). Amygdala function is important in mediating this preconditioned approach-reward stereotypic strategy, which does not involve spatial or associative memory or depend upon a learned response (McDonald and White, 1993;White and McDonald, 2002).…”
Section: Discussionmentioning
confidence: 99%
“…the sequence of maze arms entered on each session day. It has been shown that rodents with impaired spatial memory will utilize a stereotypic response strategy (i.e., successively entering adjacent arms) in searching for bait rewards that manifests as preference for choice of direction (Lanke et al, 1993). Here, preweaning Mn-exposed male rats exhibited a stereotypic response strategy on a significantly greater number of session days compared to controls (Kruskal-Wallis Chi-Square 5 8.47, DF 5 2, P 5 0.01) (Fig.…”
Section: Preweaning Mn Exposure Caused a Shift In Goal-oriented Behavmentioning
confidence: 99%
“…For each rat, four randomly selected arms were selected and baited with food; no more than two adjacent arms were baited. The partially baited RAM was preferred over the all-arms-baited RAM to prevent stereotypic behaviors (e.g., visiting arms sequentially; see Lanke et al 1993) and to allow operational measurements of reference and working memory (Olton et al 1979). In the first six sessions, food pellets were placed along the arms as well as at the end of the arms; performance during these trials were not scored.…”
Section: Methodsmentioning
confidence: 99%