Pipe network adjustment is a very important in the design of water supply network. Taking a annular pipe network in a county as an example, it expounds how to apply Guan Lide software to pipeline layout, pipe network adjustment calculation, fire protection, and accident verification. The results show that when designing water supply networks, using Guan Lide to arrange pipelines is more convenient, reducing the labor intensity of designers, and providing convenient and reliable references for designers in pipe diameter, pump selection, and other aspects in hydraulic calculations such as pipe network adjustment and verification, to further optimize the design of water supply networks. When using this software for water supply network adjustment calculation, it has the characteristics of less preparation work for network adjustment, not limited by the number of pipe sections, rings, and water sources, reliable and convenient adjustment of calculation results, and intuitive display of hydraulic elements of nodes and pipe sections.