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Background: Previous studies have demonstrated that the combination of computerized cognitive training (CCT) and aerobic exercise produces more significant therapeutic effects on cognitive function compared to either intervention alone. However, its impact on specific cognitive domains remains unclear.Objective: This study was aim to investigate the rehabilitative effects of computerized cognitive training combined with aerobic exercise on cognitive domains in patients with post-stroke cognitive impairment (PSCI) using objective indicators.Methods: This randomized controlled trial was conducted at a tertiary hospital in northern China, recruiting 134 participants with PSCI who were randomly assigned to either the control group (n=67) or the intervention group (n=67) using an opaque envelope method. Both groups received 30-minute interventions five times a week. Changes in cognitive domains, global cognitive function, activities of daily living, stroke severity, and quality of life (QOL) were compared prior to the intervention, at 3 months, and at 6 months post-intervention. Results: Of the 109 participants who completed the full intervention and follow-up, analysis of the 5 cognitive function variables revealed a significant group × time interaction for all variables except visuospatial ability, favoring the intervention group (global cognitive function [Wald c2=26.437, P<0.001], memory [Wald c2=67.781, P<0.001], attention [Wald c2=12.174, P=0.002], execution [Wald c2=136.341, P<0.001], visuospatial ability [Wald c2=3.755, P=0.153]). Additionally, both activities of daily living and QOL also showed significant group × time interactions, favoring the intervention group. Conclusions: The combination of CCT and aerobic exercise effectively enhanced the cognitive function of patients with PSCI, particularly in the areas of memory, attention, and execution. Moreover, it improved activities of daily living and QOL. Clinical Trial: Clinical trial registration: ChiCTR2300076646.
Background: Previous studies have demonstrated that the combination of computerized cognitive training (CCT) and aerobic exercise produces more significant therapeutic effects on cognitive function compared to either intervention alone. However, its impact on specific cognitive domains remains unclear.Objective: This study was aim to investigate the rehabilitative effects of computerized cognitive training combined with aerobic exercise on cognitive domains in patients with post-stroke cognitive impairment (PSCI) using objective indicators.Methods: This randomized controlled trial was conducted at a tertiary hospital in northern China, recruiting 134 participants with PSCI who were randomly assigned to either the control group (n=67) or the intervention group (n=67) using an opaque envelope method. Both groups received 30-minute interventions five times a week. Changes in cognitive domains, global cognitive function, activities of daily living, stroke severity, and quality of life (QOL) were compared prior to the intervention, at 3 months, and at 6 months post-intervention. Results: Of the 109 participants who completed the full intervention and follow-up, analysis of the 5 cognitive function variables revealed a significant group × time interaction for all variables except visuospatial ability, favoring the intervention group (global cognitive function [Wald c2=26.437, P<0.001], memory [Wald c2=67.781, P<0.001], attention [Wald c2=12.174, P=0.002], execution [Wald c2=136.341, P<0.001], visuospatial ability [Wald c2=3.755, P=0.153]). Additionally, both activities of daily living and QOL also showed significant group × time interactions, favoring the intervention group. Conclusions: The combination of CCT and aerobic exercise effectively enhanced the cognitive function of patients with PSCI, particularly in the areas of memory, attention, and execution. Moreover, it improved activities of daily living and QOL. Clinical Trial: Clinical trial registration: ChiCTR2300076646.
BACKGROUND Previous studies have demonstrated that the combination of computerized cognitive training (CCT) and aerobic exercise produces more significant therapeutic effects on cognitive function compared to either intervention alone. However, its impact on specific cognitive domains remains unclear. OBJECTIVE This study was aim to investigate the rehabilitative effects of computerized cognitive training combined with aerobic exercise on cognitive domains in patients with post-stroke cognitive impairment (PSCI) using objective indicators. METHODS This randomized controlled trial was conducted at a tertiary hospital in northern China, recruiting 134 participants with PSCI who were randomly assigned to either the control group (n=67) or the intervention group (n=67) using an opaque envelope method. Both groups received 30-minute interventions five times a week. Changes in cognitive domains, global cognitive function, activities of daily living, stroke severity, and quality of life (QOL) were compared prior to the intervention, at 3 months, and at 6 months post-intervention. RESULTS Of the 109 participants who completed the full intervention and follow-up, analysis of the 5 cognitive function variables revealed a significant group × time interaction for all variables except visuospatial ability, favoring the intervention group (global cognitive function [Wald c2=26.437, P<0.001], memory [Wald c2=67.781, P<0.001], attention [Wald c2=12.174, P=0.002], execution [Wald c2=136.341, P<0.001], visuospatial ability [Wald c2=3.755, P=0.153]). Additionally, both activities of daily living and QOL also showed significant group × time interactions, favoring the intervention group. CONCLUSIONS The combination of CCT and aerobic exercise effectively enhanced the cognitive function of patients with PSCI, particularly in the areas of memory, attention, and execution. Moreover, it improved activities of daily living and QOL. CLINICALTRIAL Clinical trial registration: ChiCTR2300076646.
Importance: Spatial neglect (SN)—failure to respond to stimuli on the side of the body contralateral to a poststroke lesion—is one of the most disabling impairments for stroke survivors, and 80% of stroke survivors may have undetected SN. Occupational therapists’ evaluations should include determining the impact of poststroke SN. Objective: To investigate occupational therapists’ confidence, knowledge, current practices, barriers, and facilitators when assessing for SN in adult stroke survivors. Design: A 30-item survey was created with guidance from stroke rehabilitation occupational therapists who reviewed the survey for face and content validity. Setting: Online survey. Participants: Occupational therapist survey responders (N = 76). Outcomes and Measures: Self-report assessments were used to measure occupational therapists’ confidence in identifying SN, SN assessment practices, and barriers to and facilitators of SN assessment. Knowledge of SN signs and symptoms, neuroanatomy, and clinical presentation were measured with a three-question quiz. Results: Eighty-one percent of the respondents reported a high level of confidence in identifying SN, and 70% reported routinely assessing for SN, with 81% using clinical observation rather than standardized tools as the primary assessment method. Barriers to SN assessment included time and resources. Conclusions and Relevance: Most respondents, despite reporting high levels of confidence with routine SN assessments, did not use standardized SN measures and demonstrated suboptimal knowledge of SN. These results emphasize the need to increase clinical education about SN and its assessments. Plain-Language Summary: This study gathered baseline information on an underinvestigated topic—occupational therapists’ education, confidence, current practices, barriers, and facilitators when assessing for spatial neglect in adult stroke survivors. The study results also contribute to future research on occupational therapists’ current confidence and knowledge when assessing for spatial neglect.
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