Strategic asset allocation requires the investor to select stocks from a given basket of assets and to weight those. Bayesian regularization is shown to not only provide stock selection but also optimal sequential portfolio weights. The perspective of the investor is to maximize alpha risk-adjusted returns relative to a benchmark index. Incorporating investor's preferences using regularization is performed using the approach related to Black and Litterman (1992) and Puelz et al. (2015). We show how to tailor MCMC algorithms to calculate portfolio weights and perform selection. We illustrate our methodology with an application to stock selection from SP100, top fifty holdings of Renaissance Technologies and Viking Global portfolios. Finally, we conclude with directions for future research.