2011
DOI: 10.1093/bioinformatics/btr034
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SpaCEM3: a software for biological module detection when data is incomplete, high dimensional and dependent

Abstract: Summary: Among classical methods for module detection, SpaCEM3 provides ad hoc algorithms that were shown to be particularly well adapted to specific features of biological data: high-dimensionality, interactions between components (genes) and integrated treatment of missingness in observations. The software, currently in its version 2.0, is developed in C++ and can be used either via command line or with the GUI under Linux and Windows environments.Availability: The SpaCEM3 software, a documentation and datas… Show more

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Cited by 3 publications
(4 citation statements)
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“…Solutions exist in such cases. Some procedures using the EM approach are implemented in the SpacEM 3 software (Vignes et al, 2011) available at http://spacem3.gforge.inria.fr. Finally, since image analysis is a vast domain in terms of both methodology and applications, many important contributions are not cited or mentioned in this chapter.…”
Section: Discussionmentioning
confidence: 99%
“…Solutions exist in such cases. Some procedures using the EM approach are implemented in the SpacEM 3 software (Vignes et al, 2011) available at http://spacem3.gforge.inria.fr. Finally, since image analysis is a vast domain in terms of both methodology and applications, many important contributions are not cited or mentioned in this chapter.…”
Section: Discussionmentioning
confidence: 99%
“…The third category is based on statistical models 36 . Ambroise et al 36 proposed a spatial clustering method based on Markov random field, which was first used for image segmentation 43 proposed a software SpaCEM3 in which spatial clustering using Markov models is implemented. This software applied the model for gene clustering based on the Markov models proposed by 44 .…”
Section: Related Workmentioning
confidence: 99%
“…The Markov random field was simulated using the SpaceEM 3 software (Vignes et al . 2011). Simulation relies on 100 Gibbs sampling iterations.…”
Section: Assessment Of β Estimates Yielded By Vbemmentioning
confidence: 99%
“…For each set of parameters, 50 simulated data sets are generated, yielding an estimate ˆ for each of them. The Markov random field was simulated using the SpaceEM 3 software (Vignes et al 2011). Simulation relies on 100 Gibbs sampling iterations.…”
Section: Assessment Of Estimates Yielded By Vbemmentioning
confidence: 99%