Space radiation effects on plant and mammalian cells

Arena, Carmen; Micco, Veronica De; Macaeva, Ellina; Quintens, Roel

doi:10.1016/j.actaastro.2014.05.005

Cited by 75 publications

(63 citation statements)

References 110 publications

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“…, ; Arena et al . ). Microgravity, being considered less constraining in the case of missions targeted to the long‐term permanence in planetary outposts, radiation remains the main stressor to plant survival for space exploration.…”

Section: Introductionmentioning

confidence: 97%

Suitability of Solanum lycopersicum L. ‘Microtom’ for growth in Bioregenerative Life Support Systems: exploring the effect of high‐LET ionising radiation on photosynthesis, leaf structure and fruit traits

et al. 2019

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The realisation of manned space exploration requires the development of Bioregenerative Life Support Systems (BLSS). In such self-sufficient closed habitats, higher plants have a fundamental role in air regeneration, water recovery, food production and waste recycling. In the space environment, ionising radiation represents one of the main constraints to plant growth.• In this study, we explore whether low doses of heavy ions, namely Ca 25 Gy, delivered at the seed stage, may induce positive outcomes on growth and functional traits in plants of Solanum lycopersicum L. 'Microtom'. After irradiation of seed, plant growth was monitored during the whole plant life cycle, from germination to fruit ripening. Morphological parameters, photosynthetic efficiency, leaf anatomical functional traits and antioxidant production in leaves and fruits were analysed.• Our data demonstrate that irradiation of seeds with 25 Gy Ca ions does not prevent achievement of the seed-to-seed cycle in 'Microtom', and induces a more compact plant size compared to the control. Plants germinated from irradiated seeds show better photochemical efficiency than controls, likely due to the higher amount of D1 protein and photosynthetic pigment content. Leaves of these plants also had smaller cells with a lower number of chloroplasts. The dose of 25 Gy Ca ions is also responsible for positive outcomes in fruits: although developing a lower number of berries, plants germinated from irradiated seeds produce larger berries, richer in carotenoids, ascorbic acid and anthocyanins than controls.• These specific traits may be useful for 'Microtom' cultivation in BLSS in space, in so far as the crew members could benefit from fresh food richer in functional compounds that can be directly produced on board.Plant Biology 21 (2019) 615-626

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Section: Introductionmentioning

confidence: 97%

Suitability of Solanum lycopersicum L. ‘Microtom’ for growth in Bioregenerative Life Support Systems: exploring the effect of high‐LET ionising radiation on photosynthesis, leaf structure and fruit traits

et al. 2019

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“…At the molecular level, it is generally considered that cell killing has been mainly attributed to the radiation energy deposition in the DNA within the nucleus, with production of DNA double-strand breaks (DSB) 1 6 . Hence, the hypothesis is raised that the nuclear DNA is the critical target to induce lethal effects as a result of radiation exposure, which is termed “targeted effects” 7 8 9 . In addition, some new radiobiological experiments show that, there exist “non-targeted effects” 10 , such as bystander effect 11 12 , adaptive response 13 14 , low dose hyper-radiosensitivity 15 , etc, which do not depend on the amount of energy deposited in DNA.…”

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confidence: 99%

A generalized target theory and its applications

Zhao

et al. 2015

Sci Rep

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Different radiobiological models have been proposed to estimate the cell-killing effects, which are very important in radiotherapy and radiation risk assessment. However, most applied models have their own scopes of application. In this work, by generalizing the relationship between “hit” and “survival” in traditional target theory with Yager negation operator in Fuzzy mathematics, we propose a generalized target model of radiation-induced cell inactivation that takes into account both cellular repair effects and indirect effects of radiation. The simulation results of the model and the rethinking of “the number of targets in a cell” and “the number of hits per target” suggest that it is only necessary to investigate the generalized single-hit single-target (GSHST) in the present theoretical frame. Analysis shows that the GSHST model can be reduced to the linear quadratic model and multitarget model in the low-dose and high-dose regions, respectively. The fitting results show that the GSHST model agrees well with the usual experimental observations. In addition, the present model can be used to effectively predict cellular repair capacity, radiosensitivity, target size, especially the biologically effective dose for the treatment planning in clinical applications.

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“…Research carried out until today, have confirmed the stimulating effect of low doses of X-rays in many species of plants, also corroborated that their effectiveness depends not only on the integral dose of radiation absorbed by the vegetal organism, but also a series of interrelated biological or environmental factors that can enhance or diminish this stimulatory effect [2]. This marked susceptibility of the stimulating effect of different types of factors suggested to study the response of plants to the combination of ionizing radiation with some plant hormones; corroborating a synergistic response of auxins, gibberellins, cytokinins, abscisic acid and ethylene with low doses of X-rays [3], reversing a great importance from the theoretical and practical point of view.…”

Section: Introductionmentioning

confidence: 91%

Synergistic Effect of Low Doses of X-rays and Biobras-16 on Yield and Its Components in Tomato (<i>Solanum lycopersicum</i> L.) Plants

Serrano¹

2015

BIO

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Abstract:In Cuba the low tomato crop yield lead to the search for new alternatives to sustainably increase yields. Therefore, the aim of this study was to evaluate the synergistic effect of low doses of X-rays and Biobras-16 on the increased yield and its components in tomato plants as well as select the optimal combination for use in agriculture. Fresh seeds of the variety of tomato var. Vyta, were exposed to single and combined treatment with X-ray dose of 5, 10, 15, 20 and 25 Gy and Biobras-16 in concentrations of 0.5; 1.0; 1.5 and 2.0 mg.L -1 . The experiments were conducted during the months of October to January 2007-2010. The results showed that the combination of 20 and 25 Gy dose of X-rays and 1.5 and 2.0 mg.L -1 Biobras-16 caused a stimulating effect on yield and its components in tomato plants. Also, in this investigation was determined that the optimal treatment to achieve a synergistic effect on yield per plant was 30 Gy + 2.0 mg.L -1 , which induced increases in yield and its components. Our results suggested that low doses of x-rays and Biobras-16 have the potential to improve crop productivity of tomato plants through the improvement of plant yield and yield components.

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Space radiation effects on plant and mammalian cells

Cited by 75 publications

References 110 publications

Suitability of Solanum lycopersicum L. ‘Microtom’ for growth in Bioregenerative Life Support Systems: exploring the effect of high‐LET ionising radiation on photosynthesis, leaf structure and fruit traits

Suitability of Solanum lycopersicum L. ‘Microtom’ for growth in Bioregenerative Life Support Systems: exploring the effect of high‐LET ionising radiation on photosynthesis, leaf structure and fruit traits

A generalized target theory and its applications

Synergistic Effect of Low Doses of X-rays and Biobras-16 on Yield and Its Components in Tomato (<i>Solanum lycopersicum</i> L.) Plants

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Space radiation effects on plant and mammalian cells

Cited by 75 publications

References 110 publications

Suitability of Solanum lycopersicum L. ‘Microtom’ for growth in Bioregenerative Life Support Systems: exploring the effect of high‐LET ionising radiation on photosynthesis, leaf structure and fruit traits

Suitability of Solanum lycopersicum L. ‘Microtom’ for growth in Bioregenerative Life Support Systems: exploring the effect of high‐LET ionising radiation on photosynthesis, leaf structure and fruit traits

A generalized target theory and its applications

Synergistic Effect of Low Doses of X-rays and Biobras-16 on Yield and Its Components in Tomato (&lt;i&gt;Solanum lycopersicum&lt;/i&gt; L.) Plants

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Synergistic Effect of Low Doses of X-rays and Biobras-16 on Yield and Its Components in Tomato (<i>Solanum lycopersicum</i> L.) Plants