Mixed vaginitis is escalating worldwide and complicates the diagnosis and treatment of vaginitis. Several risk factors have been associated with prevalence of vaginitis. Prevalence and associated risk factors of different types of vaginitis especially, aerobic vaginitis (AV) are less known. A cross-sectional study was conducted to compare the prevalence and association among different types of vaginitis and risk factors in reproductive aged women (n=300) visiting Jinnah Hospital, Lahore for complaints of vaginal discharge. Data HIGHLIGHTS • Aerobic vaginitis (AV) is a least explored disease in Pakistan.• AV is the predominant cause of vaginitis followed by bacterial vaginosis (BV), vulvovaginal candidiasis (VVC) and trichomonas vaginitis (TV).• AV co-occurs significantly in higher frequency with BV and VVC as compared to TV.• Patients with history of miscarriage are more prone to AV and BV.• Unawareness and low socioeconomic conditions predispose women to TV.