Soy protein and chronic kidney disease: An updated review

Rafieian-Kopaei, Mahmoud; Beigrezaei, Sara; Nasri, Hamid; Kafeshani, Marzieh

doi:10.4103/ijpvm.ijpvm_244_17

Cited by 17 publications

(4 citation statements)

References 33 publications

(32 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the evidence is limited, some relevant studies can support the current study’s findings. The potential kidney benefits of soy products have attracted widespread public health attention in recent years ( 32 ), because soy or beans are considered good representative sources of plant-based proteins ( 33 ). Some studies found that a high-quality plant-based diet can delay CKD progression, protect the endothelium, and decrease proteinuria ( 34 , 35 ).…”

Section: Discussionmentioning

confidence: 99%

Relationships of beans intake with chronic kidney disease in rural adults: A large-scale cross-sectional study

Dong

Liao

et al. 2023

Front. Nutr.

View full text Add to dashboard Cite

Background and aimsDietary factors play an important role in the development of chronic kidney disease (CKD). However, evidence on the relationship of beans consumption with CKD remains limited and inconclusive, especially in the middle-and low-income populations. The current study aimed to investigate the relationships of beans intake with indicators of kidney injury and CKD prevalence in rural adults.MethodsA total of 20,733 rural adults from the Henan Rural Cohort Study in 2018–2022 were included. The total beans intake was collected using a validated food frequency questionnaire. Indicators of kidney injury and CKD was determined by the estimated glomerular filtration rate and the urinary albumin to creatinine ratio. Generalized linear regression and logistic regression models were applied to estimate the relationship of beans intake with continuous and dichotomized indicators of renal function, respectively.ResultsOf the 20,733 participants, 2,676 (12.91%) subjects were identified as CKD patients. After adjusting for potential confounders, participants in the higher quartiles of beans intake had a lower prevalence of CKD (odds ratio and 95% confidence interval, OR (95%CI); Q2: 0.968(0.866–1.082); Q3: 0.836(0.744–0.939); Q4: 0.854(0.751–0.970)) and albuminuria (Q2: 0.982(0.875–1.102); Q3: 0.846(0.750–0.954); Q4: 0.852 (0.746–0.973)), compared with the Q1. Per 50 g/day increment in beans intake was significantly associated with a 5 and 4% decreased prevalence of albuminuria and CKD, respectively. These inverse relationships were also significant in the subgroups of men, elder, and high-income participants (p < 0.05).ConclusionDietary beans intake was inversely associated with the prevalence of albuminuria and CKD in rural adults, suggesting that promoting soy food intake might help reduce the occurrence of CKD in rural adults.

show abstract

Section: Discussionmentioning

confidence: 99%

Relationships of beans intake with chronic kidney disease in rural adults: A large-scale cross-sectional study

Dong

Liao

et al. 2023

Front. Nutr.

View full text Add to dashboard Cite

show abstract

“…In this sense, several studies have shown that excessive consumption of proteins produces an increase in the volume and weight of the kidney, acting as a physiological modulator and also prompting a temporary increase in glomerular filtration, which is one of the factors in the fast progression of kidney disease or kidney failure [ 3 , 10 , 11 , 12 , 13 , 14 ]. Similarly, when diets with a high protein content are adhered to, the amount of urea in the blood rises, leading to renal overload, which could cause kidney function loss in the long run [ 3 , 11 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

High-Protein Processed Foods: Impact on Diet, Nutritional Status, and Possible Effects on Health

Ortega,

Arribas-López,

Salas-González

et al. 2024

Nutrients

View full text Add to dashboard Cite

Proteins are macronutrients with multiple health benefits, but excessive consumption can negatively affect health. This study aimed to evaluate the characteristics of a sample of high-protein processed foods (HPPFs), describe how their consumption affects dietary balance, and acquire knowledge of the consumption patterns of these products in a Spanish population. A sample of HPPFs available in supermarkets and on websites was collected. The contribution to recommended protein intakes was calculated using national and international references and considering the single consumption of the HPPFs and the product plus 150 g of meat. Furthermore, an online survey was conducted among a convenience sample. A total of 36 enriched protein products were evaluated. The percentage of proteins in these products ranges from 10 to 88%. The contribution of the protein recommended intake was within a range of 87.4–306.6% and 66.4–232.8% (women and men, respectively), only considering the additional proteins from 150 g of meat. One hundred thirty-nine participants completed the survey; 67.6% affirmed that they had consumed HPPFs, and half consumed them without following any consumption control. Since these products are accessible to everyone in supermarkets and protein intake is generally higher than the recommended limits, regulating the mass sale of HPPFs is essential to ensure they do not lead to protein overconsumption.

show abstract

“…Chronic kidney disease (CKD) is a major health problem with a high economic burden to healthcare systems all over the world [1,2,3], with a higher global prevalence (11–13%) than diabetes mellitus (8.2%) [3]. It is defined by the presence of a marker of kidney damage such as proteinuria or a reduced estimated glomerular filtration rate (eGFR < 60 mL/min/1.73 m 2 ) for at least three months [4].…”

Section: Introductionmentioning

confidence: 99%

“…Other CKD risk factors include smoking [5], nephron loss due to aging and renal senescence [6,7], congenital anomalies of the anatomy and function of the kidney [8], preterm birth and low birthweight [6], and acute kidney injury [6]. The annual mortality rate attributable to CKD is estimated to be approximately one million cases worldwide [1]. Higher rates of CKD prevalence have been reported from developed areas including Europe, USA, Canada, and Australia in comparison with developing countries such as Saharan Africa and India [9].…”

Section: Introductionmentioning

confidence: 99%

Impact of Gut Dysbiosis on Neurohormonal Pathways in Chronic Kidney Disease

et al. 2019

View full text Add to dashboard Cite

Chronic kidney disease (CKD) is a worldwide major health problem. Traditional risk factors for CKD are hypertension, obesity, and diabetes mellitus. Recent studies have identified gut dysbiosis as a novel risk factor for the progression CKD and its complications. Dysbiosis can worsen systemic inflammation, which plays an important role in the progression of CKD and its complications such as cardiovascular diseases. In this review, we discuss the beneficial effects of the normal gut microbiota, and then elaborate on how alterations in the biochemical environment of the gastrointestinal tract in CKD can affect gut microbiota. External factors such as dietary restrictions, medications, and dialysis further promote dysbiosis. We discuss the impact of an altered gut microbiota on neuroendocrine pathways such as the hypothalamus–pituitary–adrenal axis, the production of neurotransmitters and neuroactive compounds, tryptophan metabolism, and the cholinergic anti-inflammatory pathway. Finally, therapeutic strategies including diet modification, intestinal alpha-glucosidase inhibitors, prebiotics, probiotics and synbiotics are reviewed.

show abstract

Soy protein and chronic kidney disease: An updated review

Cited by 17 publications

References 33 publications

Relationships of beans intake with chronic kidney disease in rural adults: A large-scale cross-sectional study

Relationships of beans intake with chronic kidney disease in rural adults: A large-scale cross-sectional study

High-Protein Processed Foods: Impact on Diet, Nutritional Status, and Possible Effects on Health

Impact of Gut Dysbiosis on Neurohormonal Pathways in Chronic Kidney Disease

Contact Info

Product

Resources

About