Sources of Carbon and Energy used by Coprinus lagopus sensu Buller

Moore, David

doi:10.1099/00221287-58-1-49

Cited by 21 publications

(7 citation statements)

References 8 publications

(6 reference statements)

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“…However, they are also unable to utilize fructose whereas this sugar is one of the preferred carbon sources of the wild-type (Moore, 1969). These usually favour growth of the wild-type progeny which form one of the expected recombinant classes.…”

Section: Introductionmentioning

confidence: 99%

Genetic fine structure, site clustering and marker effect in theftrcistron ofCoprinus

Moore

1972

Genet. Res.

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Mutants in the ftr cistron of the Basidiomycete Coprinus lagopus have a lesion in sugar transport. Fifty-two alleles are placed in an allele map using recombination frequencies obtained from over 400 heteroallelic crosses. The mutant sites in the allele map are distinctly clustered into three approximately equally spaced regions. It is demonstrated that the clustering is not due to any mutational specificity. Evidence is presented which indicates that the clusters are functionally differentiated both within themselves and from one another. Additivity of recombination frequencies was good over the whole of the allele map and there was no overall map expansion. However, specific marker effect sites could be recognized. The data indicate that marker effect may act to enhance or reduce recombination frequency and that enhancement is equal and opposite to reduction. It is also shown that marker effect enhancement is only observed when the interval being mapped exceeds a certain minimum value, but that there was no upper limit to the size of the interval. Expression of marker effect was influenced both by the background genome and by the nature of the mutation at the second site in the heteroallelic cross. It is suggested that current models of recombination do not adequately explain these data and, more importantly, that their reliance on initial breakage of DNA strands in the formation of hybrid DNA creates grave mechanical difficulties. A model for genetic recombination is proposed in which the sequence of events is: (i) separation of intact double helices into single strands; (ii) illegitimate pairing between single strands from non-sister chromatids; (iii) strand breakage and exchange of covalent links so as to legitimize the illegitimately paired regions. The model allows for the formation of hybrid DNA either with or without coincident chiasmata. It is envisaged that the error recognized by any excision-repair system involved in recombination is the tangled strands at each end of the illegitimately paired region rather than base mismatching; and that the exchange of covalent links in stage (iii) involves the excision and replacement of segments of DNA.

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Section: Introductionmentioning

confidence: 99%

Genetic fine structure, site clustering and marker effect in theftrcistron ofCoprinus

Moore

1972

Genet. Res.

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“…If this were so, growth would only be comparable to that in glucose medium alone (Table 1). A similar report has been made for Coprinus lagopus by MOORE (1969). These observations confirm the fact that the fungus grows well on its natural habitat because the latter contains a mixture of carbon sources some of which will not normally be well utilized if supplied alone in a chemically defined medium in the laboratory.…”

Section: Discussionmentioning

confidence: 99%

“…Coprinus, have received some attention (FRIES 1953, MADELIN 1956and MOORE 1969. The wood-rotting basidiomycetes are known to be fungi of economic importance in that they cause nations a loss of revenue by destroying valuable timber.…”

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confidence: 99%

Studies on the carbon nutrition of Coriolopsis occidentalis (Klotzsch) Murr

Fawole

1973

J of Basic Microbiology

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Studies on the carbon nutrition of Coriolopsis occidentalis ( KLOTZSCH) MURR. M. 0. FAWOLE (Eingegangen a m 9.10. 1972)A study has been made of the carbon nutrition of Coriolopis occidentalis using carbohydrates, amino acids, and their related compounds in liquid growth medium. Of the simple carbohydrates tested, the oligosaocharides supported growth best followed by xylose. Cellulose supported fair growth as a sole carbon source but its substituted compounds were ineffective. Growth was also fair on amino acids as sole carbon sources but was largely improved in the presence of equimolar amounts of glucose.

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“…The low activity observed in glycerol-grown mycelia contrasts with the results of Gancedo et al (1967), who found that PyK activity in Candida utilis was high on glycerol and glucose. However, glycerol is, at best, an extremely poor source of carbon and energy for Coprinus lagopus (Moore, 1969) so that the low activity on this compound is not particularly surprising.…”

Section: Eflect Of Carbon Source On Total Pyk Activitymentioning

confidence: 99%

Factors Affecting the Level and Activity of Pyruvate Kinase from Coprinus lagopus sensu Buller

Stewart

Moore

1971

Journal of General Microbiology

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SUMMARYThe specific activity of Coprinus lagopus pyruvate kinase is high under conditions of glycolysis but low under conditions of gluconeogenesis. Only a single form of the enzyme was detectable, the properties of which resemble in a number of respects those of the allosteric forms of pyruvate kinase. These properties include co-operative interactions with phosphoenolpyruvate (PEP), ATP and fructose I ,6-diphospate. Fructose I ,6-diphosphate (FDP) almost completely reverses the inhibitory effects of ATP.The decrease in substrate co-operativity in the presence of FDP, the allosteric activator and the increase in ATP co-operativity in the presence of activator suggests the enzyme can be classed as a 'K-system' allosteric protein. The regulatory properties of Coprinus Zagopus pyruvate kinase (ATP-pyruvate phosphotransferase, EC 2.7. I .40) are discussed in relation to differences in allosteric pyruvate kinases from other sources.

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Sources of Carbon and Energy used by Coprinus lagopus sensu Buller

Cited by 21 publications

References 8 publications

Genetic fine structure, site clustering and marker effect in theftrcistron ofCoprinus

Genetic fine structure, site clustering and marker effect in theftrcistron ofCoprinus

Studies on the carbon nutrition of Coriolopsis occidentalis (Klotzsch) Murr

Factors Affecting the Level and Activity of Pyruvate Kinase from Coprinus lagopus sensu Buller

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