Sources, dynamics in vivo, and application of astaxanthin and lutein in laying hens: A review

Shi, Hanyi; Deng, Xuejuan; Ji, Xiaoyu; Liu, Ning; Hui-nong, Cai

doi:10.1016/j.aninu.2023.02.008

Cited by 6 publications

(4 citation statements)

References 136 publications

(187 reference statements)

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“…Lutein is another important carotenoid [45]. It is used for the pigmentation of animal tissues and products [46]. It also shows bioactive beneficial properties in chronic diseases, such as cataracts, atherosclerosis, blindness, or decreased vision [47][48][49].…”

Section: Carotenoidsmentioning

confidence: 99%

Microalgae as a Sustainable Source of Antioxidants in Animal Nutrition, Health and Livestock Development

Mavrommatis,

Tsiplakou,

Zerva

et al. 2023

Antioxidants

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Microalgae are a renewable and sustainable source of bioactive compounds, such as essential amino acids, polyunsaturated fatty acids, and antioxidant compounds, that have been documented to have beneficial effects on nutrition and health. Among these natural products, the demand for natural antioxidants, as an alternative to synthetic antioxidants, has increased. The antioxidant activity of microalgae significantly varies between species and depends on growth conditions. In the last decade, microalgae have been explored in livestock animals as feed additives with the aim of improving both animals’ health and performance as well as product quality and the environmental impact of livestock. These findings are highly dependent on the composition of microalgae strain and their amount in the diet. The use of carbohydrate-active enzymes can increase nutrient bioavailability as a consequence of recalcitrant microalgae cell wall degradation, making it a promising strategy for monogastric nutrition for improving livestock productivity. The use of microalgae as an alternative to conventional feedstuffs is becoming increasingly important due to food–feed competition, land degradation, water deprivation, and climate change. However, the cost-effective production and use of microalgae is a major challenge in the near future, and their cultivation technology should be improved by reducing production costs, thus increasing profitability.

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Section: Carotenoidsmentioning

confidence: 99%

Microalgae as a Sustainable Source of Antioxidants in Animal Nutrition, Health and Livestock Development

Mavrommatis,

Tsiplakou,

Zerva

et al. 2023

Antioxidants

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“…Polar carotenoids have a unique ability to modulate membrane stability by inserting themselves vertically into the lipid bilayers and anchoring on both sides of the bilayers. , Moreover, polar carotenoids can not only alter micropolarity but also change the phase transition temperature of the membrane, significantly impacting the overall stability and integrity of the membrane. , Lutein is a typical carotenoid with conjugated double bonds in its long chain. There are hydroxyl groups at both ends of ketone ring, and the difference of orientation and spatial position affects the structural stability of lipid bilayer. , In addition, lutein exhibits a range of physiological functions such as antioxidant, anticancer, and anti-inflammatory properties, making it an attractive additive in the food, pharmaceutical, and cosmetic industries. , The unique properties of lutein make it a promising candidate to replace cholesterol in liposomes.…”

Section: Introductionmentioning

confidence: 99%

“… 24 , 27 In addition, lutein exhibits a range of physiological functions such as antioxidant, anticancer, and anti-inflammatory properties, making it an attractive additive in the food, pharmaceutical, and cosmetic industries. 28 , 29 The unique properties of lutein make it a promising candidate to replace cholesterol in liposomes.…”

Section: Introductionmentioning

confidence: 99%

Lutein-Based pH and Photo Dual-Responsive Novel Liposomes Coated with Ce6 and PTX for Tumor Therapy

Shen,

Zhang,

Wang

et al. 2023

ACS Omega

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Liposomes are considered the best nanocarrier for delivering cancer drugs such as chlorin e6 (Ce6) and paclitaxel (PTX). However, the poor stability and non-selectivity release of liposomes may severely limit their further applications. In this study, based on the characteristics of lutein (L) photo-response and orthoester (OE) acid-response, stable and dual-responsive liposomes (Dr-lips) have been prepared. The Dr-lips exhibited a spherical shape with a uniform size of approximately 58.27 nm. Moreover, they displayed a zeta potential ranging from −45.45 to −28.25 mV and showed excellent storage stability, indicating stable colloidal properties. Additionally, they achieved high drug encapsulation rates, with 92.27% for PTX and 90.34% for Ce6, respectively. Meanwhile, under near-infrared (NIR) light at 660 nm, Ce6 plays a key role in accelerating the photodegradation rate of lutein and PEG-OE-L while also enhancing tissue penetration ability. Additionally, Dr-lips loaded with Ce6 and PTX not only displayed excellent pH and photo dual-responsiveness for targeted delivering and releasing but also showed remarkable reactive oxygen species (ROS) generation capacity and impressive anti-tumor activity in vitro. Therefore, it provides a novel strategy for optimizing stability and enhancing their targeted drug delivery of liposome.

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“…More importantly, lutein is a critical antioxidant for plants and animals [ 4 ]. Lutein in the body tissues was shown to have beneficial effects on the visual, nervous, cardiovascular, urinary, and immune systems [ 5 , 6 ]. Several latest studies reported that lutein improved oocytes, embryo quality, fertilization rate, and 2-cell blastocyst in the polycystic ovary syndrome model of mice [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of dietary lutein on the egg production, fertility, and oxidative injury indexes of aged hens

Liu¹,

Ji²,

Song³

et al. 2023

Anim Biosci

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Objective: The present study aimed to investigate the effect of dietary lutein on egg production, follicles, reproductive hormones, fertility, hatchability, and oxidative injury indexes of hens.Methods: Treatments consisted of a control diet (CON) and three lutein-supplementing diets at 25 (L1), 50 (L2), or 75 (L3) mg/kg of diet. Egg production was measured using 576 Arbor Acres breeder hens at 61 to 65 wk and follicles grades, reproductive hormones, fertility, hatchability, tissue lutein contents, and oxidative injury indexes were determined at 65 wk.Results: The results showed that at 65 wk, lutein- supplementing diets increased (p<0.05) egg production, follicular grades, fertility, hatchability, estradiol (E2), luteinizing hormone, progesterone (PROG), lutein content in the serum and yolk, compared to CON. L2 and L3 showed more pronounced (p<0.05) effects on egg production, PROG, and yolk lutein content than L1. With the increase of lutein doses from 25 to 75 mg/kg, there were linear increases (p<0.05) in egg production, lutein content, and PROG, and a quadratic trend (p<0.05) in E2. For the oxidative injury products, lutein-supplementing diets decreased (p<0.05) malondialdehyde (MDA) and protein carbonyl (PCO) in the serum, MDA and 8-hydroxy 2 deoxyguanosine (8-OHdG) in the yolk. There were linear decreases (p<0.05) in 8-OHdG in the serum, MDA, PCO, and 8-OHdG in the yolk, a quadratic trend (p<0.05) on serum 8-OHdG.Conclusion: It is concluded that lutein supplementation can improve egg production and fertility by beneficially regulating reproductive hormones and oxidative status in aged hens.

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Sources, dynamics in vivo, and application of astaxanthin and lutein in laying hens: A review

Cited by 6 publications

References 136 publications

Microalgae as a Sustainable Source of Antioxidants in Animal Nutrition, Health and Livestock Development

Microalgae as a Sustainable Source of Antioxidants in Animal Nutrition, Health and Livestock Development

Lutein-Based pH and Photo Dual-Responsive Novel Liposomes Coated with Ce6 and PTX for Tumor Therapy

Effect of dietary lutein on the egg production, fertility, and oxidative injury indexes of aged hens

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