Sorting Technology for Mesenchymal Stem Cells from a Single Tissue Source

Feng, Xinyi; Qi, Fangfang; Wang, Hailin; Li, Wenzhen; Gan, Yuyang; Qi, Caiyu; Lin, Zhen; Chen, Lu; Wang, Piao; Hu, Zhiqi; Miao, Yong

doi:10.1007/s12015-023-10635-w

Stem Cell Rev and Rep

2023

DOI: 10.1007/s12015-023-10635-w

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Sorting Technology for Mesenchymal Stem Cells from a Single Tissue Source

Xinyi Feng,

Fangfang Qi,

Hailin Wang

et al.

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2024

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Mesenchymal-Stem-Cell-Based Therapy against Gliomas

Santillán-Guaján,

Shahi,

Castresana

2024

Cells

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Glioblastoma is the most aggressive, malignant, and lethal brain tumor of the central nervous system. Its poor prognosis lies in its inefficient response to currently available treatments that consist of surgical resection, radiotherapy, and chemotherapy. Recently, the use of mesenchymal stem cells (MSCs) as a possible kind of cell therapy against glioblastoma is gaining great interest due to their immunomodulatory properties, tumor tropism, and differentiation into other cell types. However, MSCs seem to present both antitumor and pro-tumor properties depending on the tissue from which they come. In this work, the possibility of using MSCs to deliver therapeutic genes, oncolytic viruses, and miRNA is presented, as well as strategies that can improve their therapeutic efficacy against glioblastoma, such as CAR-T cells, nanoparticles, and exosomes.

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Mesenchymal-Stem-Cell-Based Therapy against Gliomas

Santillán-Guaján,

Shahi,

Castresana

2024

Cells

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Sorting Technology for Mesenchymal Stem Cells from a Single Tissue Source

Cited by 1 publication

References 103 publications

Mesenchymal-Stem-Cell-Based Therapy against Gliomas

Mesenchymal-Stem-Cell-Based Therapy against Gliomas

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