Sorption of medical preparations by chitosan

Abstract

The article provides information about sorption properties of crab chitosan in relation to Analgin, Aspirin, Quamatel, Mydocalm, Paracetamol, Tsifran and Phtalazol. Quantitative determination of medicines’ amount before and after sorption was performed by HPLC-MS method with the preliminary plotting of calibration curves. The sorption capacity of chitosan taken in different concentrations was determined. Sorption isotherms and kinetic curves of medications’ sorption by chitosan were plotted. It has been shown that the maximum degree of sorption in static conditions for all studied medicines was achieved within an hour after the beginning of the sorption process.

Chitin-chitosan complex from Rhizopus oryzae obtained on a pea culture medium, and some of its physicochemical properties

“…It was found before [15] that the largest amount of biomass of the fungus R. oryzae provides the culture media of the following composition, g/L: pea -50; glucose -5.0; (NH 4 ) 2 SO 4 -10.0, the maximum biomass concentration is reached on the third day of cultivation.…”