Sonographische Milzgrößenbestimmung: Normalmaße beim milzgesunden Erwachsenen

Frank, Kirsten; Linhart, P; Kortsik, C.; Wohlenberg, Holger

doi:10.1055/s-2007-1011931

Cited by 60 publications

(18 citation statements)

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“…in their study of a Chinese population suggested an upper limit of normal length of 12 cm. Some textbooks of ultrasound and other studies suggested an average splenic length of 12 cm, average width of 5 cm, and average depth (antero-posterior dimension) of 7 cm 1222–25. These observations suggest that there is no significant racial bias of spleen size in this study as compared with Caucasians.…”

Section: Discussionsupporting

confidence: 57%

“…The intercostal spaces were used as scan window, for proper visualization of the entire spleen. All measurements were made on sections through the splenic hilum in order to create a constant reference point for repeating measurement according to the guidelines of the American Institute of Ultrasound in Medicine12 and as described by Lamb et al 19. Splenic length (the maximum distance between the dome of the spleen and the splenic tip) was done on the longitudinal section.…”

Section: Methodsmentioning

confidence: 99%

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Determination of normal dimension of the spleen by ultrasound in an endemic tropical environment

Ogbeide

Tagbo

2011

Niger Med J

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Background:To determine the normal dimensions of spleen by ultrasonography in our environment exposed to endemic tropical infection and infestation.Materials and Methods:A prospective study of normal spleen ultrasound-based measurements in 200 Nigerian adults at the University of Benin Teaching Hospital Benin, Nigeria.Results:There were 91 males and 109 females; their age ranged between 20 and 60 years. For the males the mean age was 32.4 years (± 9.2 SD), mean height was 175.0 cm (±7.3 SD), mean weight was 72.5 kg (±10.1 SD), and mean body mass index was 23.6 (±2.8 SD) and the females the mean age was 29.7 years (±9.0 SD) mean height was 164.6 cm (±5.8 SD), mean weight 64.1 kg (±12.9 SD), and mean BMI was 24.9 (±1.4 SD). For the males the mean splenic length, width, depth, and volume were 11.1 cm (±0.9 SD), 4.4 cm (±0.5 SD), 7.8 cm (±0.6 SD), and 202.7 cm3 (±49.4 SD), respectively. For the females the corresponding values of splenic length, width, depth, and volume were 10.1 cm (±0.7 SD), 4.0 cm (±0.4 SD), 7.1 cm (±0.5 SD), and 153.7 cm3 (±33.2 SD), respectively.Conclusion:Comparison between mean splenic dimension parameters for males and females (from unpaired t-test determination) showed a statistically significant difference (P<0.001 for splenic length, width, depth, and volume). There was also statistically significant increasing value correlation between subjects’ weight and height (in favor of height) when compared to spleen length, width, depth, and volume. The other parameters show no significant correlation in both female and male. In particular there was also no statistically significant correlation of splenic measurements with age in either sex. This is similar to what was noted in other centers.

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Section: Discussionsupporting

confidence: 57%

Section: Methodsmentioning

confidence: 99%

Determination of normal dimension of the spleen by ultrasound in an endemic tropical environment

Ogbeide

Tagbo

2011

Niger Med J

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“…We also calculated the AST/ALT ratio. Splenomegaly was diagnosed when spleen length exceeded 12 cm at ultrasound examination (43). Alcohol consumption was defined as drinking more than 30 g per day of alcohol for at least 6 months.…”

Section: Methodsmentioning

confidence: 99%

A Simple Noninvasive Score Based on Routine Parameters can Predict Liver Cirrhosis in Patients With Chronic Hepatitis C

et al. 2013

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BackgroundLiver biopsy has remained the gold standard for the diagnosis of chronic hepatitis C; even though, it has a low but non-negligible rate of both false negative and complications. Several authors have proposed noninvasive tools to diagnose cirrhosis. But none of them showed complete concordance with liver biopsy.ObjectivesTo devise a score based on noninvasive routine parameters that discriminate between patients with a high risk, and those with a low risk of cirrhosis among patients with chronic hepatitis C without performing liver biopsy, and to compare this score with other ones using routine parameters devoted to this aim.Patients and MethodsWe reviewed the charts of patients with chronic hepatitis C who performed a liver biopsy between 2000 and 2004. Multivariate analysis was used to identify independent predictors of cirrhosis. An independent group of patients with chronic hepatitis C admitted for a liver biopsy between 2007 and 2012 constituted the validation set.ResultsWe enrolled 249 patients who had complete laboratoristic data, and sufficient liver tissue for fibrosis staging. Age, AST, prothrombin activity, and platelets were identified as independent predictors of histological cirrhosis. We categorized these variables, and devised a novel score called CISCUN (Cirrhosis Score University of Naples), giving one point to each of the following predictors: age > 40 years; AST > 2 upper normal values; platelet count < 160.000/mmc; prothrombin activity < 100%. Cirrhosis rate was 2.9% for the 103 patients with a CISCUN = 0 or 1, 23.4% for the 124 patients with a CISCUN of 2 or 3, and 86.4% for the 22 patients with a CISCUN = 4. These results were confirmed in the independent validation group of 285 patients with similar characteristics.ConclusionsPatients with chronic hepatitis C and with a CISCUN ≤ 1 had a very low rate of cirrhosis while those with a CISCUN = 4 had a high risk of cirrhosis. Patients with CISCUN = 2 or 3 had an intermediate rate of cirrhosis, and therefore needed to perform a liver biopsy to receive a reliable diagnosis.

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“…If a histological assessment was not available, liver cirrhosis was diagnosed based on clinical, laboratory, and imaging findings, comprising a platelet count of less than 100 000/μL, and ultrasound findings, which include a blunted nodular liver edge and splenomegaly (> 12 cm), the presence of varices, and complications of liver cirrhosis such as ascites and hepatic encephalopathy . Spleen diameter was measured using sonography or computed tomography (CT).…”

Section: Methodsmentioning

confidence: 99%

Using transient elastography to predict hepatocellular carcinoma recurrence after radiofrequency ablation

Lee

Park

Kim

et al. 2017

J of Gastro and Hepatol

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Sonographische Milzgrößenbestimmung: Normalmaße beim milzgesunden Erwachsenen

Cited by 60 publications

References 0 publications

Determination of normal dimension of the spleen by ultrasound in an endemic tropical environment

Determination of normal dimension of the spleen by ultrasound in an endemic tropical environment

A Simple Noninvasive Score Based on Routine Parameters can Predict Liver Cirrhosis in Patients With Chronic Hepatitis C

Using transient elastography to predict hepatocellular carcinoma recurrence after radiofrequency ablation

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