Sonographic evaluation of bile duct size during pregnancy

Mintz, Marshall C.; Grumbach, Kathryn; Arger, Peter H.; Coleman, Beverly G.

doi:10.2214/ajr.145.3.575

Cited by 12 publications

(2 citation statements)

References 8 publications

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“…There b a lso a decreased rnte O 1) a nd percentage ( H, 33) of emptying. The common bile Juel size remains within normal limits (34).…”

Section: Pathogenesis Of Gallstone Formation In Pregnancymentioning

confidence: 93%

Pregnancy and the Biliary System

Witt¹,

Connon²

1990

Canadian Journal of Gastroenterology and Hepatology

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Alterations in the synthesis and secretion of bile salts and cholesterol and in gallbladder function occur during pregnancy. These changes are related to the effects of estrogen and progesterone. Biliary cholesterol saturation and the cholic acid/chenodeoxycholic acid ratio increase. Progesterone also diminishes gallbladder contractility and emptying. Gallstones occur in 2.5 to 11% of pregnant women and are associated with cholecystitis in 0.008 to 0.1% of pregnant women. Operative treatment should be deferred if possible until after delivery; failing that, surgery is best done in the second trimester. Endoscopic pap1llotomy may prove to be the best therapy for choledocholithiasis.

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