Sonographic Detection and Sonographically Guided Biopsy of Breast  Microcalcifications

Soo, Mary Scott; Baker, Jay A.; Rosen, Eric L.

doi:10.2214/ajr.180.4.1800941

Cited by 166 publications

(158 citation statements)

References 11 publications

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“…A possible explanation for the present results is that the 11-guage vacuumassisted biopsies incorporated a higher proportion of calcified lesions (18/24, 75%) compared to 14-gauge automated gun biopsies (14/50, 28%). In our institution, the calcification is also subjected to vacuum-assisted biopsy under ultrasound guidance when lesions are evident on sonography because sampling the sonographically visible component often helps target the invasive component [15,25,26]. Such calcified lesions were a significant causal factor for underestimation not only in our study but also other studies [1,27].…”

Section: Discussionmentioning

confidence: 54%

Scoring system for predicting malignancy in patients diagnosed with atypical ductal hyperplasia at ultrasound-guided core needle biopsy

Han

Lee

et al. 2007

Breast Cancer Res Treat

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Background The aim of this study was to determine factors that predict under-evaluation of malignancy in patients diagnosed with atypical ductal hyperplasia (ADH) at ultrasound-guided core needle biopsy (CNB), and to develop a prediction algorithm for scoring the possibility of a diagnosis upgrade to malignancy based on clinical, radiological and pathological factors. Methods The study enrolled patients diagnosed with ADH at ultrasound-guided CNB who subsequently underwent surgical excision of the lesion. Multivariate analysis was used to identify relevant clinical, radiological and pathological factors that may predict malignancy. Results A total of 102 patients with ADH at CNB were identified. Of the 74 patients who underwent subsequent surgical excision, 34 (45.8%) were diagnosed with invasive or in situ malignant foci. Multivariate analysis revealed that age [50 years, microcalcification on mammography, size on imaging [15 mm and a palpable lesion were independent predictors of malignancy. Focal ADH was a negative predictor. A scoring system was developed based on logistic regression models and beta coefficients for each variable. The area under the ROC curve was 0.903 (95% CI: 0.82-0.94), and the negative predictive value was 100% for a score B3.5. Similar findings were observed for a validation dataset of 54 patients at other institutions. Conclusions A scoring system to predict malignancy in patients diagnosed with ADH at CNB was developed based on five factors: age, palpable lesion, microcalcification on mammography, size on imaging and focal ADH. This system was able to identify a subset of patients with lesions likely to be benign, indicating that imaging follow-up rather than surgical excision may be appropriate.

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Section: Discussionmentioning

confidence: 54%

Scoring system for predicting malignancy in patients diagnosed with atypical ductal hyperplasia at ultrasound-guided core needle biopsy

Han

Lee

et al. 2007

Breast Cancer Res Treat

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“…Estudos têm sido realizados na intenção de demonstrar a capacidade de a ultra-sonografia guiar procedimentos invasivos em microcalcificações agrupadas (CLEVERLEY et al, 1997;HUANG et al, 1999;TEH et al, 2000;MOON et al, 2000;SOO et al, 2002;SOO et al, 2003) com resultados promissores.…”

Section: Biópsias Percutâneas Orientadas Pela Ultra-sonografiaunclassified

“…Em geral, as alterações encontradas nesta categoria são maiores e quase sempre relacionadas à malignidade. Para Soo e colaboradores (SOO et al, 2003), este número foi de 89%.…”

Section: Ultra-som E Bi-radsunclassified

“…Das pacientes com ultra-sonografia positiva, classificadas como BI-RADS categoria 4, 18,2% eram câncer (4/22). Na avaliação de Soo e colaboradores (SOO et al, 2003), 59% dos focos vistos na ultra-sonografia, categoria 4, eram positivos para malignidade. Estes valores estão discordantes e podem refletir uma interpretação diversa para os critérios propostos por ACR -BI-RADS.…”

Section: Ultra-som E Bi-radsunclassified

“…Vários estudos (TEH et al, 2000;GUFLER et al, 2000;SOO et al, 2003) (GUFLER et al, 2000), na sua casuística, obtiveram sensibilidade de 100% na identificação de microcalcificações nos casos positivos para malignidade -carcinomas ductais "in situ" e invasivos.…”

Section: Casos Positivos Para Câncerunclassified

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Ultra-sonografia mamária na identificação e orientação de biópsia percutânea das microcalcificações agrupadas

Castro¹

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Value of specimen radiographs in diagnosing multifocality of thyroid cancer

Kwak

Kim

Hong

et al. 2010

British Journal of Surgery

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Sonographic Detection and Sonographically Guided Biopsy of Breast Microcalcifications

Abstract: Suspicious microcalcifications are seen infrequently on sonography (23%) but, when detected, can be successfully biopsied with sonographic guidance and more frequently are malignant and represent invasive cancer than those seen on mammography alone.

Cited by 166 publications

References 11 publications

Scoring system for predicting malignancy in patients diagnosed with atypical ductal hyperplasia at ultrasound-guided core needle biopsy

Scoring system for predicting malignancy in patients diagnosed with atypical ductal hyperplasia at ultrasound-guided core needle biopsy

Ultra-sonografia mamária na identificação e orientação de biópsia percutânea das microcalcificações agrupadas

Value of specimen radiographs in diagnosing multifocality of thyroid cancer

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