Sonographic demonstration of multiple intrahepatic meconium masses in a newborn with meconium peritonitis

Ries, M.; Kh, Deeg

doi:10.1111/j.1651-2227.1994.tb18292.x

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…After title and abstract screening, 56 studies were selected for full-text analysis. Fourteen manuscripts met the inclusion criteria and were included for data analysis [2,7,[12][13][14][15][16][19][20][21][22][23][24]. The addition of our institutional findings resulted in a total of 15 studies.…”

Section: Results From Meta-analysismentioning

confidence: 99%

Fetal Meconium Peritonitis – Prenatal Findings and Postnatal Outcome: A Case Series, Systematic Review, and Meta-Analysis

et al. 2020

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Purpose To describe the postnatal outcome of fetal meconium peritonitis and identify prenatal predictors of neonatal surgery. Methods We retrospectively reviewed all fetuses with ultrasound findings suspicious for meconium peritonitis at a single center over a 10-year period. A systematic review and meta-analysis were then performed pooling our results with previous studies assessing prenatally diagnosed meconium peritonitis and postnatal outcome. Prenatal sonographic findings were analyzed to identify predictors for postnatal surgery. Results 34 cases suggestive of meconium peritonitis were diagnosed at our center. These were pooled with cases from 14 other studies yielding a total of 244 cases. Postnatal abdominal surgery was required in two thirds of case (66.5 %). The strongest predictor of neonatal surgery was meconium pseudocyst (OR [95 % CI] 6.75 [2.53–18.01]), followed by bowel dilation (OR [95 % CI] 4.17 [1.93–9.05]) and ascites (OR [95 % CI] 2.57 [1.07–5.24]). The most common cause of intestinal perforation and meconium peritonitis, found in 52.2 % of the cases, was small bowel atresia. Cystic fibrosis was diagnosed in 9.8 % of cases. Short-term neonatal outcomes were favorable, with a post-operative mortality rate of 8.1 % and a survival rate of 100 % in neonates not requiring surgery. Conclusion Meconium pseudocysts, bowel dilation, and ascites are prenatal predictors of neonatal surgery in cases of meconium peritonitis. Fetuses with these findings should be delivered in centers with pediatric surgery services. Though the prognosis is favorable, cystic fibrosis complicates postnatal outcomes.

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Section: Results From Meta-analysismentioning

confidence: 99%

Fetal Meconium Peritonitis – Prenatal Findings and Postnatal Outcome: A Case Series, Systematic Review, and Meta-Analysis

et al. 2020

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“…Less commonly, hepatic hemangioendotheliomas can manifest as dilated intrahepatic vessels with a concurrent elevated maternal α-fetoprotein level (63). Intrahepatic meconium pseudocysts may be considered in the appropriate clinical context and appear as multiple complex intrahepatic cysts (64). Finally, simple hepatic cysts and arteriovenous malformations and fistulas have the expected US characteristics (65).…”

Section: Benign and Malignant Fetal Hepatic Tumorsmentioning

confidence: 99%

Fetal Hepatomegaly: Causes and Associations

Jensen

Patel

et al. 2020

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Fetal hepatomegaly is associated with significant fetal morbidity and mortality. However, hepatomegaly might be overlooked when numerous other fetal anomalies are present, or it might not be noticed when it is an isolated entity. As the largest solid organ in the abdomen, the liver can be seen well with US or MRI, and the normal imaging characteristics are well described. The length of the fetal liver, which can be used to identify hepatomegaly, can be determined by measuring the liver from the diaphragm to the tip of the right lobe in the sagittal plane. Fetal hepatomegaly is seen with infection, transient abnormal myelopoiesis, liver storage and deposition diseases, some syndromes, large liver tumors, biliary atresia, and anemia. Some of these diagnoses are treatable during the fetal period. Attention to the associated findings and specific hepatic and nonhepatic imaging characteristics can help facilitate more accurate diagnoses and appropriate patient counseling. © RSNA, 2020 • radiographics.rsna.org

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“…Die multiplen intrahepatischen zystischen Veränderungen bei Patient 6 sind ein seltener sonographischer Befund [27]. Wahrscheinlich hat nach der Perforation im Colon transversum die entzündliche Reaktion des Mekoniums einschließlich der Verdauungsenzyme zu einer Ruptur der Leberkapsel mit intrahepatischer Ausbreitung des Mekoniums geführt.…”

Section: Introductionunclassified