Sonographic assessment of uterine and ovarian development in normal girls aged 1 to 12 years

Abstract

There is a continuous increase in size of internal female genitalia from early childhood until the onset of puberty. We have provided reference percentile charts of normal uterine length, uterine volume, and ovarian volume in girls aged 1-12 years.

Ovarian and uterine ultrasonography and relation to puberty in healthy girls between 6 and 16 years in the Turkish population: a cross-sectional study

“…In our study, maximum TUL was found to be 4.5 cm in prepubertal girls and the cut-off value for TUL was 4 cm, where sensitivity of 53 % and specifi city of 55 % were considered to be cutoff levels in differentiating prepubertal and pubertal girls in our population. Our study is in agreement with other studies revealing similar results in other countries (5,6,13,15,19) .…”

Ovarian and uterine development and hormonal feedback mechanism in a 46 XX patient with CYP19A1 deficiency under low dose estrogen replacement

“…Comparison of our findings with their data is shown in Figure 1. Comparison with smaller studies analyzing data from girls up to 14 years shows similar results [11,14,17]. Not including our patient, we identified 17 other cases of 46, XX DSD, aromatase deficiency [5,9,[18][19][20][21][22][23][24][25][26][27][28][29].…”

Early Polycystic Ovary Syndrome as a Possible Etiology of Unexplained Premenarcheal Ovarian Torsion

“…Two patients had a calculable ovarian volume of 28.5 cm 3 and 7.2 cm 3 on preoperative ultrasound, which was significantly greater than the expected volumes of 1.8 cm 3 AE 0.8 and 2.6 cm 3 AE 0.9 for a 10-and 11-year-old, respectively. 15,16 Two other cases had measurements performed intraoperatively by the surgeon and were noted to be 4 Â 5 cm (or a maximal area of 16.0 cm 2 ) and 8 Â 9 cm (or maximal area of 57.6 cm 2 ). Interestingly, in all four cases the ultrasonographer or the surgeon commented on the contralateral ovary appearing polycystic and significantly enlarged.…”

“…12,17 Even in the adolescent girl who did not meet volume criteria for PCOS, her volume of 7.2 cm 3 was still significantly enlarged when compared to her age group, which has an average of 2.6 cm 3 AE 0.9. 16 Furthermore, in the one case where a wedge biopsy was performed, the ovary was noted to have extensive hilar fibrosis possibly due to an increase in ovarian stroma as seen in PCOS. 17 Also, when comparing the adult population, the only significantly enlarged contralateral ovary was noted in a woman with PCOS.…”