Sonochemical synthesis of chromenes catalyzed by L-phenyl alanine-attached nano-Fe₃O₄@SiO₂

Abstract

An efficient multi-component synthesis of 10,10-dimethyl-7-(phenyl)-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H )-diones is described by a one-pot condensation reaction of aldehydes, dimedone and 4-hydroxycoumarin using L-phenyl alanine tethered to nano-Fe 3 O 4 @SiO 2 under ultrasonic irradiation. The catalyst has been characterized by Fourier-transform infrared spectroscopy (FT-IR), X-ray powder diffraction (XRD), scanning electron microscope (SEM), Energy-dispersive X-ray spectroscopy (EDX), thermal gravimetric analysis (TGA) and vibratingsample magnetometer (VSM). Atom economy, wide range of products, high catalytic activity, excellent yields in short reaction times, reusability of the catalyst and low catalyst loading are some of the important features of this protocol. ARTICLE HISTORY

Green and eco-friendly mica/Fe3O4as an efficient nanocatalyst for the multicomponent synthesis of 2-amino-4H-chromene derivatives

“…Recently, magnetic nanoparticles (MNPs) owing to their considerable properties such as their relatively low cost, suitable reactive sites, high specific surface area and easy separation have been applied in various branches of sciences [1][2][3][4]. The surface of MNPs is typically modified or coated with renewable polymers, carbon materials, silica compounds and clay minerals to improve their colloidal stability and reduce their toxicity [5][6][7][8][9]. The obtained magnetic nanocomposites can be used in various fields including medical therapy and diagnosis, adsorption and catalysis [10][11][12][13][14].…”