The cobalt chromium molybdenum (Co-Cr-Mo) system composes speci c alloys used in several biomedical applications, mainly in implants and prostheses manufacturing. Due to its intrinsic properties, the alloy processing is known as hard-to-machine. Therefore, in this work, we machined the Co-Cr-Mo alloy ASTM F75 and analyzed the effects of the cutting parameters on tool wear and the surface roughness generated during the turning. We performed a complete factorial with two factors, levels and replicas, in which the cutting speed varied from 60 to 90 m.min -1 and the feed rate from 0.08 to 0.13 mm.rev -1 . Through Scanning Electron Microscopy (SEM) and confocal microscopy analysis, we quanti ed wear on the cutting tool and the surface roughness of specimens. During the morphological studies, we noted the presence of crater and ank wear, with crater wear being predominant. This crater wear was exclusively in uenced by the change in feed rate due to the loss of tool coating. Moreover, the changes in cutting parameters signi cantly in uenced both cutting tool wear and workpiece surface roughness. The extreme cutting parameters caused signi cant differences in peak and valleys height on the turned workpiece surface. This way, the average roughness is strongly affected by the increase in tool wear induced by cutting parameters during the process. By energy dispersion spectroscopy (EDXA), we identi ed the chemical elements on the worn tool and workpiece surfaces which revealed that the primary mechanism causing tool wear is workpiece material adhesion to the insert rake surface. Furthermore, we con rmed the presence of carbides embedded on the machined surface, indicating abrasive action of these particles during cutting.