Some serum biochemical and pathological changes in squabs of domestic pigeons (Columba Livia) infected with Trichomonas

Abstract

The present study was carried out to represent a field problem in squabs of domestic pigeons (columba livia) at Ismailia Province. Squabs were grossly examined and showed typical lesions including yellowish caseous, fibronecrotic patches in mouth due to infection with T. gallinae. Forty squabs were collected and tested individually for the presence of Trichomonas gallinae (T. gallinae). Squabs were divided into equal four groups, the 1 st was un-infected control group, the 2 nd was T. gallinae infected untreated group, the 3 rd and the 4 th groups were T. gallinae infected and treated with metronidazole. The obtained results showed that the mortality (%) were 0, 50, 20 and 30 % in 1 st , 2 nd , 3 rd and 4 th group, respectively. Body weight was significantly reduced in all groups, although the drugs improved the weight reduction as compared to pre-treatment. Organs' weights were significantly increased after treatment as compared with the control group. Serum biochemical analysis revealed significant elevation in total protein, globulins; β-globulin and γglobulin but albumin , α-globulin levels and A/G ratio were significantly reduced in infected squabs and increased in treated groups. Serum urea, creatinine and uric acid levels were increased, while, Serum glucose , cholesterol Na, K, Ca, P, Mg and serum iron as well as plasma ChE activity were decreased in both treated and infected groups. Serum AST, ALT, LD, γ -GGT, CK, AP activities were significantly increased in infected groups, Destructive changes in buccal cavity, hyperemia in blood vessels, necrotic changes in the liver with leucocytic infiltration and demylination of brain with preivascular oedema were observed. Veterinary MedicalJournal

Prevalence Study of Trichomonas gallinae in Domestic Pigeons in Northeastern Beijing and Experimental Model of Trichomoniasis in White King Squabs Measuring In Situ Apoptosis and Immune Factors in Crop and Esophagus

“…Many previous studies have focused on the morphology, epidemiology and pathology [3][4][5][6][7][8][9]13,[15][16][17][18][19], but there are only a few on the level of in situ apoptosis and immune factors in experimentally infected squabs. Cell apoptosis is a manifestation of host self-protection and an important factor in regulating parasite-induced host immune responses [20].…”