“…On these regimens, the levels of urinary MMA were between 7.6 and 13.9mg/mg of creatinine in case 1 and between 1.8 and 5.5 mg/mg ofcreatinine in case 2, and both patients showed no ketoacidosis. The amounts of valine, isoleucine, threonine and methionine in these formulas bordered on or were below the minimal daily requirement (Holt 1968), especially in case 2. However, these patients displayed physical and mental development, and no symptoms suggestive of protein malnutrition such as failure to thrive, change in hair colour, loss of hair, skin pigmentation, or edema associated with hypoalbuminemia were observed.…”