Some Pharmacological Studies on Marbofloxacin and Flunixin Muglumine Combination During Treatment of Coliform Mastitis in Cattle

Abstract

The aim of the present work was to study the effect of Marbofloxacin with Flunixin Muglumine combination during treatment of coliform mastitis in cattle. Twenty coliform mastitic cows were selected from 50 mastitic cows and treated by Marbofloxacin and Flunixin muglumine. The results showed that the red blood cell (RBC) count and hemoglobin concentration were significantly decreased. Similar changes were observed with the mean corpuscular volume and total platelets. Meanwhile, White blood cell (WBC) count was significantly elevated. There are no significant changes recorded in serum albumin and globulin with tested drugs throughout the study. However, there is a significant increase in serum total proteins. The result recorded also, a significant increase (in serum aspartate aminotransferase (AST) and serum alkaline phosphatase (ALP)) and a significant decrease in serum alanine aminotransferase (ALT) was recorded.