Some Novel Amino Acid-Schiff Bases and their Complexes Synthesis, Characterization, Solid State Conductivity Behaviors and Potentiometric Studies

Abstract

Three new Schiff bases derived from the condensation reaction of thiophene-2-carbaldehyde and DL-alanine, DL-valine and DL-phenylalanine have been synthesized and their Co(II), Ni(II) and Cu(II) complexes have been prepared. The Schiff bases and the complexes have been characterized by their analytical and spectral data. The protonation constants of the Schiff bases and stability constants of the complexes have been determined potentiometrically in aqueous medium at 25 °C and 0.1 M KCl ionic strength. Solid state conductivities of the synthesized substances were using the four-probe technique on a compressed pellet at room temperature.

Spectral characterization, optical band gap calculations and DNA binding of some binuclear Schiff-base metal complexes derived from 2-amino-ethanoic acid and acetylacetone

“…The conditions which favorable the formation of amino acids Schiff base were described in some papers [9][10][11]. On the other hand, the formed organic amino acid Schiff bases are not stable and sensitive to moisture and decompose when exposed to air [12].…”

Green Route for Efficient Synthesis of Novel Amino Acid Schiff Bases as Potent Antibacterial and Antifungal Agents and Evaluation of Cytotoxic Effects

“…All the synthesized compounds were found to be chiral [44]. The occurrence of E/Z isomerism at the imine band of the molecules was suggested by Sari and Gürkan [45].…”

Synthesis and biological activity of new cycloalkylthiophene-Schiff bases and their Cr(III) and Zn(II) complexes

“…X -1 cm 2 mol -1 . This state indicated that the 1:1 electrolytic behaviour for Cr(III) (Sari and Gürkan 2004). Zn(II) complexes were nonelectrolytic.…”