Some Measures for COVID-19 Including Deep Ultraviolet Light-Emitting Diode (DUV-LED), Gc protein-derived Macrophage-Activating Factor (Gcmaf), and 5-Aminolevulinic Acid (5-ALA)

Abstract

Several trials for the COVID-19 pandemic are found. Prof. Shunji Nakamura, Tokushima University was awarded the 2014 Nobel prize in Physics for light-emitting diodes (LEDs). Deep ultraviolet LED (DUV-LED) causes SARS-CoV-2 inactivation as 99.9% by 265 nm. Gc protein-derived macrophage-activating factor (GcMAF)-based immunotherapy has a wider application for serious infection, chronic fatigue syndrome, and cancers. Covid center in Naples submitted a phase II report concerning GcMAF and COVID-19 in Feb 2021. 5-aminolevulinic acid (5-ALA) and its metabolite protoporphyrin IX (PpIX) show anti-inflammatory and antiviral effects for Zika, Dengue, influenza A viruses, and SARS-CoV-2. These results hopefully contribute to the research development for COVID-19.

Analysis of the Biological Properties of Blood Plasma Protein with GcMAF Functional Activity

“…Because of that, we chose day 16 from the experiment initiation as a time point for analysis. This was the time point (day [15][16][17] when the first sites of necrotic tumor lysis with purulent discharge were observed, indicating an active catabolic process in the tumor. Tissues and organs from the control, Karanahan therapy, and Karanahan approach plus GcMAF-RF Groups were isolated on a selected day, and cell populations were analyzed as described in the pilot study.…”

“…Numerous reports for experimental animals and data obtained in preclinical studies indicate that it is promising to use GcMAF in clinical practice. Specific properties of the macrophage activator and the positive previous experience of its clinical use have underlain the clinical trials of the preparation against COVID-19 [ 15 , 16 , 17 ].…”